Site-Specific Bioconjugation of a Murine Dihydrofolate Reductase Enzyme by Copper(I)-Catalyzed Azide-Alkyne Cycloaddition with Retained Activity

• Sung In Lim,

  Affiliation Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia, United States of America

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• Yukina Mizuta,

  Affiliation Department of Frontier Materials, Nagoya Institute of Technology, Nagoya, Aichi, Japan

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• Akinori Takasu,

  Affiliation Department of Frontier Materials, Nagoya Institute of Technology, Nagoya, Aichi, Japan

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• Yong Hwan Kim,

  Affiliation Department of Chemical Engineering, Kwangwoon University, Seoul, Republic of Korea

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• Inchan Kwon

  * E-mail: ik4t@virginia.edu

  Affiliations Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia, United States of America, School of Materials Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, Republic of Korea

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