Dissecting the Critical Factors for Thermodynamic Stability of Modular Proteins Using Molecular Modeling Approach

Yuno Lee; Joong-jae Lee; Songmi Kim; Sang-Chul Lee; Jieun Han; Woosung Heu; Keunwan Park; Hyun Jung Kim; Hae-Kap Cheong; Dongsup Kim; Hak-Sung Kim; Keun Woo Lee

doi:10.1371/journal.pone.0098243

Loading metrics

Open Access

Peer-reviewed

Research Article

Dissecting the Critical Factors for Thermodynamic Stability of Modular Proteins Using Molecular Modeling Approach

Yuno Lee ,

Contributed equally to this work with: Yuno Lee, Joong-jae Lee, Songmi Kim

Affiliation Division of Applied Life Science (BK21 Program), Systems and Synthetic Agrobiotech Center (SSAC), Plant Molecular Biology and Biotechnology Research Center (PMBBRC), Research Institute of Natural Science (RINS), Gyeongsang National University (GNU), Jinju, Korea
⨯
Joong-jae Lee ,

Contributed equally to this work with: Yuno Lee, Joong-jae Lee, Songmi Kim

Affiliation Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejon, Korea
⨯
Songmi Kim ,

Contributed equally to this work with: Yuno Lee, Joong-jae Lee, Songmi Kim

Affiliation Division of Applied Life Science (BK21 Program), Systems and Synthetic Agrobiotech Center (SSAC), Plant Molecular Biology and Biotechnology Research Center (PMBBRC), Research Institute of Natural Science (RINS), Gyeongsang National University (GNU), Jinju, Korea
⨯
Sang-Chul Lee,

Affiliation Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejon, Korea
⨯
Jieun Han,

Affiliation Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejon, Korea
⨯
Woosung Heu,

Affiliation Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejon, Korea
⨯
Keunwan Park,

Affiliation Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea
⨯
Hyun Jung Kim,

Affiliation Division of Magnetic Resonance Research, Korea Basic Science Institute, Cheongwon, Chungbuk, Korea
⨯
Hae-Kap Cheong,

Affiliation Division of Magnetic Resonance Research, Korea Basic Science Institute, Cheongwon, Chungbuk, Korea
⨯
Dongsup Kim,

Affiliation Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea
⨯
Hak-Sung Kim ,

* E-mail: hskim76@kaist.ac.kr (H-SK); kwlee@gnu.ac.kr (KWL)

Affiliation Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejon, Korea
⨯
Keun Woo Lee

* E-mail: hskim76@kaist.ac.kr (H-SK); kwlee@gnu.ac.kr (KWL)

Affiliation Division of Applied Life Science (BK21 Program), Systems and Synthetic Agrobiotech Center (SSAC), Plant Molecular Biology and Biotechnology Research Center (PMBBRC), Research Institute of Natural Science (RINS), Gyeongsang National University (GNU), Jinju, Korea
⨯

Dissecting the Critical Factors for Thermodynamic Stability of Modular Proteins Using Molecular Modeling Approach

Yuno Lee,
Joong-jae Lee,
Songmi Kim,
Sang-Chul Lee,
Jieun Han,
Woosung Heu,
Keunwan Park,
Hyun Jung Kim,
Hae-Kap Cheong,
Dongsup Kim

Published: May 21, 2014
https://doi.org/10.1371/journal.pone.0098243

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Thermodynamics
Is the Subject Area "Thermodynamics" applicable to this article?

Thanks for your feedback.
Protein structure
Is the Subject Area "Protein structure" applicable to this article?

Thanks for your feedback.
Molecular dynamics
Is the Subject Area "Molecular dynamics" applicable to this article?

Thanks for your feedback.
Crystal structure
Is the Subject Area "Crystal structure" applicable to this article?

Thanks for your feedback.
Free energy
Is the Subject Area "Free energy" applicable to this article?

Thanks for your feedback.
Protein structure comparison
Is the Subject Area "Protein structure comparison" applicable to this article?

Thanks for your feedback.
Protein interactions
Is the Subject Area "Protein interactions" applicable to this article?

Thanks for your feedback.
Antibodies
Is the Subject Area "Antibodies" applicable to this article?

Thanks for your feedback.