The Effects of a Novel Hormonal Breast Cancer Therapy, Endoxifen, on the Mouse Skeleton

Anne Gingery; Malayannan Subramaniam; Kevin S. Pitel; Jordan M. Reese; Muzaffer Cicek; Laurence B. Lindenmaier; James N. Ingle; Matthew P. Goetz; Russell T. Turner; Urszula T. Iwaniec; Thomas C. Spelsberg; John R. Hawse

doi:10.1371/journal.pone.0098219

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Open Access

Peer-reviewed

Research Article

The Effects of a Novel Hormonal Breast Cancer Therapy, Endoxifen, on the Mouse Skeleton

Anne Gingery,

Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Malayannan Subramaniam,

Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Kevin S. Pitel,

Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Jordan M. Reese,

Affiliations Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Muzaffer Cicek,

Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Laurence B. Lindenmaier,

Affiliation Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, United States of America
⨯
James N. Ingle,

Affiliation Department of Oncology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Matthew P. Goetz,

Affiliations Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States of America, Department of Oncology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Russell T. Turner,

Affiliation Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, United States of America
⨯
Urszula T. Iwaniec,

Affiliation Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, United States of America
⨯
Thomas C. Spelsberg,

Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
John R. Hawse

* E-mail: hawse.john@mayo.edu

Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯

The Effects of a Novel Hormonal Breast Cancer Therapy, Endoxifen, on the Mouse Skeleton

Anne Gingery,
Malayannan Subramaniam,
Kevin S. Pitel,
Jordan M. Reese,
Muzaffer Cicek,
Laurence B. Lindenmaier,
James N. Ingle,
Matthew P. Goetz,
Russell T. Turner,
Urszula T. Iwaniec

Published: May 22, 2014
https://doi.org/10.1371/journal.pone.0098219

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