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Open Access

Peer-reviewed

Research Article

COX-2 Protects against Atherosclerosis Independently of Local Vascular Prostacyclin: Identification of COX-2 Associated Pathways Implicate Rgl1 and Lymphocyte Networks

Nicholas S. Kirkby ,

* E-mail: n.kirkby@imperial.ac.uk (NSK); j.a.mitchell@imperial.ac.uk (JAM)

Affiliations National Heart & Lung Institute, Imperial College London, London, United Kingdom, The William Harvey Research Institute, Barts & the London School of Medicine & Dentistry, Queen Mary University of London, London, United Kingdom
⨯
Martina H. Lundberg,

Affiliations National Heart & Lung Institute, Imperial College London, London, United Kingdom, The William Harvey Research Institute, Barts & the London School of Medicine & Dentistry, Queen Mary University of London, London, United Kingdom
⨯
William R. Wright,

Affiliation National Heart & Lung Institute, Imperial College London, London, United Kingdom
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Timothy D. Warner,

Affiliation The William Harvey Research Institute, Barts & the London School of Medicine & Dentistry, Queen Mary University of London, London, United Kingdom
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Mark J. Paul-Clark,

Affiliation National Heart & Lung Institute, Imperial College London, London, United Kingdom
⨯
Jane A. Mitchell

* E-mail: n.kirkby@imperial.ac.uk (NSK); j.a.mitchell@imperial.ac.uk (JAM)

Affiliation National Heart & Lung Institute, Imperial College London, London, United Kingdom
⨯

COX-2 Protects against Atherosclerosis Independently of Local Vascular Prostacyclin: Identification of COX-2 Associated Pathways Implicate Rgl1 and Lymphocyte Networks

Nicholas S. Kirkby,
Martina H. Lundberg,
William R. Wright,
Timothy D. Warner,
Mark J. Paul-Clark,
Jane A. Mitchell

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Published: June 2, 2014
https://doi.org/10.1371/journal.pone.0098165

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Atherosclerosis
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Prostacyclin
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COX-2 inhibitors
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Gene expression
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NSAIDs
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Microarrays
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Thymus
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T cells
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