Diisopropylamine Dichloroacetate, a Novel Pyruvate Dehydrogenase Kinase 4 Inhibitor, as a Potential Therapeutic Agent for Metabolic Disorders and Multiorgan Failure in Severe Influenza

• Kazuhiko Yamane,

  Affiliation Division of Enzyme Chemistry, Institute for Enzyme Research, The University of Tokushima, Tokushima, Japan

  ⨯
• Irene L. Indalao,

  Affiliation Division of Enzyme Chemistry, Institute for Enzyme Research, The University of Tokushima, Tokushima, Japan

  ⨯
• Junji Chida,

  Affiliation Division of Enzyme Chemistry, Institute for Enzyme Research, The University of Tokushima, Tokushima, Japan

  ⨯
• Yoshikazu Yamamoto,

  Affiliation R&D Department, Daiichi Sankyo Healthcare Co., Ltd., Tokyo, Japan

  ⨯
• Masaaki Hanawa,

  Affiliation R&D Department, Daiichi Sankyo Healthcare Co., Ltd., Tokyo, Japan

  ⨯
• Hiroshi Kido

  * E-mail: kido@ier.tokushima-u.ac.jp

  Affiliation Division of Enzyme Chemistry, Institute for Enzyme Research, The University of Tokushima, Tokushima, Japan

  ⨯