Structural Insight into the Tetramerization of an Iterative Ketoreductase SiaM through Aromatic Residues in the Interfaces

Hua Wang; Huaidong Zhang; Yi Zou; Yanling Mi; Shuangjun Lin; Zhixiong Xie; Yunjun Yan; Houjin Zhang

doi:10.1371/journal.pone.0097996

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Peer-reviewed

Research Article

Structural Insight into the Tetramerization of an Iterative Ketoreductase SiaM through Aromatic Residues in the Interfaces

Hua Wang,

Affiliations Key Laboratory of Molecular Biophysics, Ministry of Education, Wuhan, Hubei, China, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Huaidong Zhang,

Affiliations Key Laboratory of Molecular Biophysics, Ministry of Education, Wuhan, Hubei, China, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Yi Zou,

Affiliation State Key Laboratory of Microbial Metabolism, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China
⨯
Yanling Mi,

Affiliations Key Laboratory of Molecular Biophysics, Ministry of Education, Wuhan, Hubei, China, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Shuangjun Lin,

Affiliation State Key Laboratory of Microbial Metabolism, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China
⨯
Zhixiong Xie,

Affiliation College of Life Sciences, Wuhan University, Wuhan, Hubei, China
⨯
Yunjun Yan,

Affiliations Key Laboratory of Molecular Biophysics, Ministry of Education, Wuhan, Hubei, China, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Houjin Zhang

* E-mail: hjzhang@hust.edu.cn

Affiliations Key Laboratory of Molecular Biophysics, Ministry of Education, Wuhan, Hubei, China, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯

Structural Insight into the Tetramerization of an Iterative Ketoreductase SiaM through Aromatic Residues in the Interfaces

Hua Wang,
Huaidong Zhang,
Yi Zou,
Yanling Mi,
Shuangjun Lin,
Zhixiong Xie,
Yunjun Yan,
Houjin Zhang

Published: June 5, 2014
https://doi.org/10.1371/journal.pone.0097996

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