Adiponectin Ameliorates Experimental Periodontitis in Diet-Induced Obesity Mice

Lan Zhang; Shu Meng; Qisheng Tu; Liming Yu; Yin Tang; Michel M. Dard; Sung-Hoon Kim; Paloma Valverde; Xuedong Zhou; Jake Chen

doi:10.1371/journal.pone.0097824

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Peer-reviewed

Research Article

Adiponectin Ameliorates Experimental Periodontitis in Diet-Induced Obesity Mice

Lan Zhang,

Affiliations Division of Oral Biology, Tufts University School of Dental Medicine, Boston, Massachusetts, United States of America, Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China
⨯
Shu Meng,

Affiliations Division of Oral Biology, Tufts University School of Dental Medicine, Boston, Massachusetts, United States of America, Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China
⨯
Qisheng Tu ,

* E-mail: jk.chen@tufts.edu (JC); qisheng.tu@tufts.edu (QT)

Affiliation Division of Oral Biology, Tufts University School of Dental Medicine, Boston, Massachusetts, United States of America
⨯
Liming Yu,

Affiliation Division of Oral Biology, Tufts University School of Dental Medicine, Boston, Massachusetts, United States of America
⨯
Yin Tang,

Affiliations Division of Oral Biology, Tufts University School of Dental Medicine, Boston, Massachusetts, United States of America, Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China
⨯
Michel M. Dard,

Affiliation Periodontology and Implant Dentistry, New York University College of Dentistry, New York, New York, United States of America
⨯
Sung-Hoon Kim,

Affiliation Cancer Preventive Material Development Research Center (CPMDRC) and Institute, College of Oriental Medicine, Kyung Hee University, Dongdaemun-gu, Seoul, Korea
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Paloma Valverde,

Affiliation Department of Sciences, Wentworth Institute of Technology, Boston, Massachusetts, United States of America
⨯
Xuedong Zhou,

Affiliation Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China
⨯
Jake Chen

* E-mail: jk.chen@tufts.edu (JC); qisheng.tu@tufts.edu (QT)

Affiliations Division of Oral Biology, Tufts University School of Dental Medicine, Boston, Massachusetts, United States of America, Department of Anatomy and Cell Biology, Tufts University School of Medicine, Sackler School of Graduate Biomedical Sciences, Boston, Massachusetts, United States of America
⨯

Adiponectin Ameliorates Experimental Periodontitis in Diet-Induced Obesity Mice

Lan Zhang,
Shu Meng,
Qisheng Tu,
Liming Yu,
Yin Tang,
Michel M. Dard,
Sung-Hoon Kim,
Paloma Valverde,
Xuedong Zhou,
Jake Chen

Published: May 16, 2014
https://doi.org/10.1371/journal.pone.0097824

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Periodontitis
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Osteoclasts
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Alveolar bone
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Inflammation
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Mouse models
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Adiponectin
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Bone resorption
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