In Vivo and In Vitro Studies Suggest a Possible Involvement of HPV Infection in the Early Stage of Breast Carcinogenesis via APOBEC3B Induction

Kenji Ohba; Koji Ichiyama; Misako Yajima; Nobuhiro Gemma; Masaru Nikaido; Qingqing Wu; PeiPei Chong; Seiichiro Mori; Rain Yamamoto; John Eu Li Wong; Naoki Yamamoto

doi:10.1371/journal.pone.0097787

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Open Access

Peer-reviewed

Research Article

In Vivo and In Vitro Studies Suggest a Possible Involvement of HPV Infection in the Early Stage of Breast Carcinogenesis via APOBEC3B Induction

Kenji Ohba,

Affiliation Infectious Disease program, Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⨯
Koji Ichiyama,

Affiliation Infectious Disease program, Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⨯
Misako Yajima,

Affiliation Infectious Disease program, Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⨯
Nobuhiro Gemma,

Affiliation TOSHIBA Research & Development Center, TOSHIBA Corporation, Kawasaki, Kanagawa, Japan
⨯
Masaru Nikaido,

Affiliation Materials and Devices Division, TOSHIBA Corporation, Minato-ku, Tokyo, Japan
⨯
Qingqing Wu,

Affiliation Infectious Disease program, Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⨯
PeiPei Chong,

Affiliations Infectious Disease program, Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor Darul Ehsan, Malaysia
⨯
Seiichiro Mori,

Affiliation Pathogen Genomics Center, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan
⨯
Rain Yamamoto,

Affiliation Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America
⨯
John Eu Li Wong,

Affiliation Department of Hematology-Medical Oncology, National University Cancer Institute, the Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⨯
Naoki Yamamoto

* E-mail: naoki_yamamoto@nuhs.edu.sg

Affiliation Infectious Disease program, Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⨯

In Vivo and In Vitro Studies Suggest a Possible Involvement of HPV Infection in the Early Stage of Breast Carcinogenesis via APOBEC3B Induction

Kenji Ohba,
Koji Ichiyama,
Misako Yajima,
Nobuhiro Gemma,
Masaru Nikaido,
Qingqing Wu,
PeiPei Chong,
Seiichiro Mori,
Rain Yamamoto,
John Eu Li Wong

Published: May 23, 2014
https://doi.org/10.1371/journal.pone.0097787

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07 Jun 2014
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Newly identified causal mechanisms in human papilloma virus associated breast cancer. Posted by jalawson on 04 Jun 2014 at 01:41 GMT

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