IQGAP3 Promotes EGFR-ERK Signaling and the Growth and Metastasis of Lung Cancer Cells

Ying Yang; Wei Zhao; Qing-Wen Xu; Xiao-Song Wang; Yu Zhang; Jun Zhang

doi:10.1371/journal.pone.0097578

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Open Access

Peer-reviewed

Research Article

IQGAP3 Promotes EGFR-ERK Signaling and the Growth and Metastasis of Lung Cancer Cells

Ying Yang ,

Contributed equally to this work with: Ying Yang, Wei Zhao

Affiliation Department of Immunology, School of Basic Medical Sciences, Key Laboratory of Medical Immunology of Ministry of Public Health, Peking University Health Science Center, Beijing, P. R. China
⨯
Wei Zhao ,

Contributed equally to this work with: Ying Yang, Wei Zhao

Current address: Department of Clinical Laboratory Medicine, China-Japan Friendship Hospital, Beijing, P. R. China

Affiliation Department of Immunology, School of Basic Medical Sciences, Key Laboratory of Medical Immunology of Ministry of Public Health, Peking University Health Science Center, Beijing, P. R. China
⨯
Qing-Wen Xu,

Affiliation Department of Immunology, School of Basic Medical Sciences, Key Laboratory of Medical Immunology of Ministry of Public Health, Peking University Health Science Center, Beijing, P. R. China
⨯
Xiao-Song Wang,

Affiliation Department of Immunology, School of Basic Medical Sciences, Key Laboratory of Medical Immunology of Ministry of Public Health, Peking University Health Science Center, Beijing, P. R. China
⨯
Yu Zhang ,

* E-mail: junzhang@bjmu.edu.cn (YZ); zhangyu007@hsc.pku.edu.cn (JZ)

Affiliation Department of Immunology, School of Basic Medical Sciences, Key Laboratory of Medical Immunology of Ministry of Public Health, Peking University Health Science Center, Beijing, P. R. China
⨯
Jun Zhang

* E-mail: junzhang@bjmu.edu.cn (YZ); zhangyu007@hsc.pku.edu.cn (JZ)

Affiliation Department of Immunology, School of Basic Medical Sciences, Key Laboratory of Medical Immunology of Ministry of Public Health, Peking University Health Science Center, Beijing, P. R. China
⨯

IQGAP3 Promotes EGFR-ERK Signaling and the Growth and Metastasis of Lung Cancer Cells

Ying Yang,
Wei Zhao,
Qing-Wen Xu,
Xiao-Song Wang,
Yu Zhang,
Jun Zhang

Published: May 21, 2014
https://doi.org/10.1371/journal.pone.0097578

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Lung and intrathoracic tumors
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Breast cancer
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Gastric cancer
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Transfection
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Immunoprecipitation
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Cancer cell migration
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Non-small cell lung cancer
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ERK signaling cascade
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