Normal Fibroblasts Induce E-Cadherin Loss and Increase Lymph Node Metastasis in Gastric Cancer

Wen Xu; Xinlei Hu; Zhongting Chen; Xiaoping Zheng; Chenjing Zhang; Gang Wang; Yu Chen; Xinglu Zhou; Xiaoxiao Tang; Laisheng Luo; Xiang Xu; Wensheng Pan

doi:10.1371/journal.pone.0097306

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Open Access

Peer-reviewed

Research Article

Normal Fibroblasts Induce E-Cadherin Loss and Increase Lymph Node Metastasis in Gastric Cancer

Wen Xu,

Affiliation Department of Gastroenterology, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China
⨯
Xinlei Hu,

Affiliation Department of Orthopedics, Second Affiliated Hospital (Binjiang Branch) of Zhejiang University, School of Medicine, Hangzhou, China
⨯
Zhongting Chen,

Affiliation Department of Pharmacy, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China
⨯
Xiaoping Zheng,

Affiliation Department of Pathology, Qujiang People’s Hospital, Quzhou, China
⨯
Chenjing Zhang,

Affiliation Department of Gastroenterology, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China
⨯
Gang Wang,

Affiliation Department of Gastroenterology, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China
⨯
Yu Chen,

Affiliation Zhejiang Academy of Traditional Chinese Medicine, Experimental Animal Research Center, Hangzhou, China
⨯
Xinglu Zhou,

Affiliation Department of Gastroenterology, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China
⨯
Xiaoxiao Tang,

Affiliation Department of Gastroenterology, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China
⨯
Laisheng Luo,

Affiliation Department of Gastroenterology, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China
⨯
Xiang Xu,

Affiliation Department of Pharmacy, Second Affiliated Hospital (Binjiang Branch) of Zhejiang University, School of Medicine, Hangzhou, China
⨯
Wensheng Pan

* E-mail: wspan223@163.com

Affiliations Department of Gastroenterology, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China, Department of Gastroenterology, Second Affiliated Hospital (Binjiang Branch) of Zhejiang University, School of Medicine, Hangzhou, China
⨯

Normal Fibroblasts Induce E-Cadherin Loss and Increase Lymph Node Metastasis in Gastric Cancer

Wen Xu,
Xinlei Hu,
Zhongting Chen,
Xiaoping Zheng,
Chenjing Zhang,
Gang Wang,
Yu Chen,
Xinglu Zhou,
Xiaoxiao Tang,
Laisheng Luo

Published: May 20, 2014
https://doi.org/10.1371/journal.pone.0097306

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Fibroblasts
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Lymph nodes
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