Prevalence of Bloodstream Pathogens Is Higher in Neonatal Encephalopathy Cases vs. Controls Using a Novel Panel of Real-Time PCR Assays

Cally J. Tann; Peter Nkurunziza; Margaret Nakakeeto; James Oweka; Jennifer J. Kurinczuk; Jackson Were; Natasha Nyombi; Peter Hughes; Barbara A. Willey; Alison M. Elliott; Nicola J. Robertson; Nigel Klein; Kathryn A. Harris

doi:10.1371/journal.pone.0097259

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Open Access

Peer-reviewed

Research Article

Prevalence of Bloodstream Pathogens Is Higher in Neonatal Encephalopathy Cases vs. Controls Using a Novel Panel of Real-Time PCR Assays

Cally J. Tann ,

* E-mail: cally.tann@lshtm.ac.uk

Affiliations Clinical Research Department, Faculty of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom, Mulago University Hospital, Kampala, Uganda
⨯
Peter Nkurunziza,

Affiliation MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda
⨯
Margaret Nakakeeto,

Affiliation Mulago University Hospital, Kampala, Uganda
⨯
James Oweka,

Affiliation MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda
⨯
Jennifer J. Kurinczuk,

Affiliation National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
⨯
Jackson Were,

Affiliation MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda
⨯
Natasha Nyombi,

Affiliation Mulago University Hospital, Kampala, Uganda
⨯
Peter Hughes,

Affiliation Institute for Women’s Health, University College London, Medical School Building, London, United Kingdom
⨯
Barbara A. Willey,

Affiliation Clinical Research Department, Faculty of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯
Alison M. Elliott,

Affiliations Clinical Research Department, Faculty of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom, MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda
⨯
Nicola J. Robertson,

Affiliation Institute for Women’s Health, University College London, Medical School Building, London, United Kingdom
⨯
Nigel Klein,

Affiliations Institute for Child Health, University College London, London, United Kingdom, Department of Microbiology, Virology and Infection Control, Great Ormond Street Hospital for Children, London, United Kingdom
⨯
Kathryn A. Harris

Affiliations Institute for Child Health, University College London, London, United Kingdom, Department of Microbiology, Virology and Infection Control, Great Ormond Street Hospital for Children, London, United Kingdom
⨯

Prevalence of Bloodstream Pathogens Is Higher in Neonatal Encephalopathy Cases vs. Controls Using a Novel Panel of Real-Time PCR Assays

Cally J. Tann,
Peter Nkurunziza,
Margaret Nakakeeto,
James Oweka,
Jennifer J. Kurinczuk,
Jackson Were,
Natasha Nyombi,
Peter Hughes,
Barbara A. Willey,
Alison M. Elliott

Published: May 16, 2014
https://doi.org/10.1371/journal.pone.0097259

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