Evolution of Direct Costs in the First Years of Rheumatoid Arthritis: Impact of Early versus Late Biologic Initiation - An Economic Analysis Based on the ESPOIR Cohort

• Karine Chevreul ,

  * E-mail: karine.chevreul@urc-eco.fr

  Affiliations URC Eco Île-de-France (AP-HP), Hôtel Dieu, Paris, France, Inserm, ECEVE, U1123, Paris, France, Univ Paris Diderot, Sorbonne Paris Cité, ECEVE, UMRS 1123, Paris, France

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• Georges Haour,

  Affiliation URC Eco Île-de-France (AP-HP), Hôtel Dieu, Paris, France

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• Sandy Lucier,

  Affiliation URC Eco Île-de-France (AP-HP), Hôtel Dieu, Paris, France

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• Stephanie Harvard,

  Affiliations URC Eco Île-de-France (AP-HP), Hôtel Dieu, Paris, France, Pierre and Marie Curie University (UPMC) – Paris 6, UPMC GRC 08, Institut Pierre Louis d’Epidémiologie et Santé Publique, Paris, France

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• Marie-Laure Laroche,

  Affiliations Pharmacology and Toxicology Unit, Centre of Pharmacovigilance-Pharmacoepidemiology CHU, Limoges, France, Limoges University, EA 6310 HAVAE, Faculty of Medicine, Limoges, France

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• Xavier Mariette,

  Affiliation Paris XI University, Department of Rheumatology, Bicêtre University Hospital (AP-HP), Le Kremlin Bicêtre, France

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• Alain Saraux,

  Affiliation Brest University, Department of Rheumatology, La Cavale Blanche Hospital, Brest, France

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• Isabelle Durand-Zaleski,

  Affiliations URC Eco Île-de-France (AP-HP), Hôtel Dieu, Paris, France, Inserm, ECEVE, U1123, Paris, France, Univ Paris Diderot, Sorbonne Paris Cité, ECEVE, UMRS 1123, Paris, France, Department of Public Health, Henri Mondor-Albert Chenevilier Hospitals (AP-HP), Créteil, France

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• Francis Guillemin,

  Affiliation Lorraine University, EA 4360 APEMAC; INSERM CIC-EC CIE6, Nancy, France

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• Bruno Fautrel

  Affiliations Pierre and Marie Curie University (UPMC) – Paris 6, UPMC GRC 08, Institut Pierre Louis d’Epidémiologie et Santé Publique, Paris, France, AP-HP, Department of Rheumatology, La Pitié Salpêtrière University Hospital, Paris, France

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