Suppression of Akt-mTOR Pathway-A Novel Component of Oncogene Induced DNA Damage Response Barrier in Breast Tumorigenesis

Anjana Bhardwaj; Daniel Rosen; Mei Liu; Yan Liu; Qiang Hao; Nivetha Ganesan; Carol J. Etzel; Ashley Gullett; Constance T. Albarracin; Isabelle Bedrosian

doi:10.1371/journal.pone.0097076

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Open Access

Peer-reviewed

Research Article

Suppression of Akt-mTOR Pathway-A Novel Component of Oncogene Induced DNA Damage Response Barrier in Breast Tumorigenesis

Anjana Bhardwaj,

Affiliation Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Daniel Rosen,

Affiliation Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Mei Liu,

Affiliation Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Yan Liu,

Affiliation Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Qiang Hao,

Affiliation Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Nivetha Ganesan,

Affiliation Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Carol J. Etzel,

Affiliation Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Ashley Gullett,

Affiliation Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Constance T. Albarracin,

Affiliation Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Isabelle Bedrosian

* E-mail: ibedrosian@mdanderson.org.

Affiliation Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯

Suppression of Akt-mTOR Pathway-A Novel Component of Oncogene Induced DNA Damage Response Barrier in Breast Tumorigenesis

Anjana Bhardwaj,
Daniel Rosen,
Mei Liu,
Yan Liu,
Qiang Hao,
Nivetha Ganesan,
Carol J. Etzel,
Ashley Gullett,
Constance T. Albarracin,
Isabelle Bedrosian

Published: May 8, 2014
https://doi.org/10.1371/journal.pone.0097076

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