Characterization of Nontypable Haemophilus influenzae Isolates Recovered from Adult Patients with Underlying Chronic Lung Disease Reveals Genotypic and Phenotypic Traits Associated with Persistent Infection

Junkal Garmendia; Cristina Viadas; Laura Calatayud; Joshua Chang Mell; Pau Martí-Lliteras; Begoña Euba; Enrique Llobet; Carmen Gil; José Antonio Bengoechea; Rosemary J. Redfield; Josefina Liñares

doi:10.1371/journal.pone.0097020

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Peer-reviewed

Research Article

Characterization of Nontypable Haemophilus influenzae Isolates Recovered from Adult Patients with Underlying Chronic Lung Disease Reveals Genotypic and Phenotypic Traits Associated with Persistent Infection

Junkal Garmendia ,

* E-mail: juncal.garmendia@unavarra.es

Affiliations Instituto de Agrobiotecnología, CSIC-Universidad Pública Navarra-Gobierno Navarra, Mutilva, Spain, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain, Laboratory Microbial Pathogenesis, Fundación Investigación Sanitaria Illes Balears, Bunyola, Spain
⨯
Cristina Viadas,

Affiliation Instituto de Agrobiotecnología, CSIC-Universidad Pública Navarra-Gobierno Navarra, Mutilva, Spain
⨯
Laura Calatayud,

Affiliations Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain, Microbiology Department, University Hospital Bellvitge, IDIBELL, University of Barcelona, Barcelona, Spain
⨯
Joshua Chang Mell,

Affiliations Department of Zoology, University British Columbia, Vancouver, British Columbia, Canada, Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Pau Martí-Lliteras,

Affiliations Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain, Laboratory Microbial Pathogenesis, Fundación Investigación Sanitaria Illes Balears, Bunyola, Spain
⨯
Begoña Euba,

Affiliations Instituto de Agrobiotecnología, CSIC-Universidad Pública Navarra-Gobierno Navarra, Mutilva, Spain, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain
⨯
Enrique Llobet,

Affiliations Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain, Laboratory Microbial Pathogenesis, Fundación Investigación Sanitaria Illes Balears, Bunyola, Spain
⨯
Carmen Gil,

Affiliation Instituto de Agrobiotecnología, CSIC-Universidad Pública Navarra-Gobierno Navarra, Mutilva, Spain
⨯
José Antonio Bengoechea,

Affiliations Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain, Laboratory Microbial Pathogenesis, Fundación Investigación Sanitaria Illes Balears, Bunyola, Spain, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
Rosemary J. Redfield,

Affiliation Department of Zoology, University British Columbia, Vancouver, British Columbia, Canada
⨯
Josefina Liñares

Affiliations Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain, Microbiology Department, University Hospital Bellvitge, IDIBELL, University of Barcelona, Barcelona, Spain
⨯

Characterization of Nontypable Haemophilus influenzae Isolates Recovered from Adult Patients with Underlying Chronic Lung Disease Reveals Genotypic and Phenotypic Traits Associated with Persistent Infection

Junkal Garmendia,
Cristina Viadas,
Laura Calatayud,
Joshua Chang Mell,
Pau Martí-Lliteras,
Begoña Euba,
Enrique Llobet,
Carmen Gil,
José Antonio Bengoechea,
Rosemary J. Redfield

Published: May 13, 2014
https://doi.org/10.1371/journal.pone.0097020

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23 Jul 2014
11:59 GMT
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Correction introduced in Acknowledgments section. Please note that this modification acknowledges the Pharmaceutical Sciences Sequencing Centre at the University of British Columbia, supported by grants from the CFI and the faculty of Pharmaceutical Sciences. Posted by jungarmendia on 23 Jul 2014 at 11:59 GMT

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Respiratory infections
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Haemophilus influenzae
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