Toward Discovering New Anti-Cancer Agents Targeting Topoisomerase IIα: A Facile Screening Strategy Adaptable to High Throughput Platform

Open Access

Peer-reviewed

Research Article

Yu-Shih Lin,

Affiliation Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan
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Wan-Chen Huang,

Affiliation Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan
⨯
Mei-Shya Chen,

Affiliation Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan
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Tao-shih Hsieh

* E-mail: thsieh@duke.edu

Affiliations Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan, Department of Biochemistry, Duke University Medical Center, Durham, North Carolina, United States of America
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Anisotropy
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DNA cleavage
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Cancer treatment
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Agarose gel electrophoresis
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Enzymes
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Glycerol
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Drug screening
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High throughput screening
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