Sorafenib Metabolism Is Significantly Altered in the Liver Tumor Tissue of Hepatocellular Carcinoma Patient

Ling Ye; Xiaoshan Yang; Enshuang Guo; Weiying Chen; Linlin Lu; Ying Wang; Xiaojuan Peng; Tongmeng Yan; Fuyan Zhou; Zhongqiu Liu

doi:10.1371/journal.pone.0096664

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Open Access

Peer-reviewed

Research Article

Sorafenib Metabolism Is Significantly Altered in the Liver Tumor Tissue of Hepatocellular Carcinoma Patient

Ling Ye ,

Contributed equally to this work with: Ling Ye, Xiaoshan Yang

Affiliations Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, China, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
⨯
Xiaoshan Yang ,

Contributed equally to this work with: Ling Ye, Xiaoshan Yang

Affiliations Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, China, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
⨯
Enshuang Guo,

Affiliations Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, China, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China
⨯
Weiying Chen,

Affiliation Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, China
⨯
Linlin Lu,

Affiliations Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, China, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
⨯
Ying Wang,

Affiliation Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, China
⨯
Xiaojuan Peng,

Affiliation Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, China
⨯
Tongmeng Yan,

Affiliation Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, China
⨯
Fuyan Zhou,

Affiliation Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China
⨯
Zhongqiu Liu

* E-mail: liuzq@smu.edu.cn

Affiliations Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, China, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
⨯

Sorafenib Metabolism Is Significantly Altered in the Liver Tumor Tissue of Hepatocellular Carcinoma Patient

Ling Ye,
Xiaoshan Yang,
Enshuang Guo,
Weiying Chen,
Linlin Lu,
Ying Wang,
Xiaojuan Peng,
Tongmeng Yan,
Fuyan Zhou,
Zhongqiu Liu

Published: May 5, 2014
https://doi.org/10.1371/journal.pone.0096664

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