Identification of the Genomic Insertion Site of Pmel-1 TCR α and β Transgenes by Next-Generation Sequencing

Yun Ji; Natalie Abrams; Wei Zhu; Eddie Salinas; Zhiya Yu; Douglas C. Palmer; Parthav Jailwala; Zulmarie Franco; Rahul Roychoudhuri; Eric Stahlberg; Luca Gattinoni; Nicholas P. Restifo

doi:10.1371/journal.pone.0096650

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Open Access

Peer-reviewed

Research Article

Identification of the Genomic Insertion Site of Pmel-1 TCR α and β Transgenes by Next-Generation Sequencing

Yun Ji ,

* E-mail: jiyun@mail.nih.gov (YJ); restifo@nih.gov (NPR)

Affiliation Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Natalie Abrams,

Affiliation Advanced Biomedical Computing Center, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America
⨯
Wei Zhu,

Affiliation Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Eddie Salinas,

Affiliation Advanced Biomedical Computing Center, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America
⨯
Zhiya Yu,

Affiliation Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Douglas C. Palmer,

Affiliation Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Parthav Jailwala,

Affiliation Advanced Biomedical Computing Center, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America
⨯
Zulmarie Franco,

Affiliation Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Rahul Roychoudhuri,

Affiliation Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Eric Stahlberg,

Affiliation Advanced Biomedical Computing Center, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America
⨯
Luca Gattinoni ,

Contributed equally to this work with: Luca Gattinoni, Nicholas P. Restifo

Affiliation Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Nicholas P. Restifo

Contributed equally to this work with: Luca Gattinoni, Nicholas P. Restifo

* E-mail: jiyun@mail.nih.gov (YJ); restifo@nih.gov (NPR)

Affiliation Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

Identification of the Genomic Insertion Site of Pmel-1 TCR α and β Transgenes by Next-Generation Sequencing

Yun Ji,
Natalie Abrams,
Wei Zhu,
Eddie Salinas,
Zhiya Yu,
Douglas C. Palmer,
Parthav Jailwala,
Zulmarie Franco,
Rahul Roychoudhuri,
Eric Stahlberg

Published: May 14, 2014
https://doi.org/10.1371/journal.pone.0096650

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