Toll-Like Receptor (TLR)-1/2 Triggering of Multiple Myeloma Cells Modulates Their Adhesion to Bone Marrow Stromal Cells and Enhances Bortezomib-Induced Apoptosis

Open Access

Peer-reviewed

Research Article

Jahangir Abdi,

Affiliation Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, the Netherlands
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Tuna Mutis,

Affiliation Department of Clinical Chemistry & Hematology, University Medical Center Utrecht, Utrecht, the Netherlands
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Johan Garssen,

Affiliation Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, the Netherlands
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Frank A. Redegeld

* E-mail: f.a.m.redegeld@uu.nl

Affiliation Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, the Netherlands
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Integrins
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Apoptosis
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Stromal cells
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Toll-like receptors
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Bone marrow cells
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Multiple myeloma
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Cloning
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Myeloma cells
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