A Natural Bacterial-Derived Product, the Metalloprotease Arazyme, Inhibits Metastatic Murine Melanoma by Inducing MMP-8 Cross-Reactive Antibodies

• Felipe V. Pereira,

  Affiliation Department of Microbiology, Immunology, and Parasitology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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• Carla A. Ferreira-Guimarães,

  Affiliation Department of Microbiology, Immunology, and Parasitology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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• Thaysa Paschoalin,

  Affiliation Department of Biophysics, EPM-UNIFESP, São Paulo, Brazil

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• Jorge A. B. Scutti,

  Affiliation Department of Microbiology, Immunology, and Parasitology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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• Filipe M. Melo,

  Affiliation Department of Microbiology, Immunology, and Parasitology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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• Luis S. Silva,

  Affiliation Department of Microbiology, Immunology, and Parasitology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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• Amanda C. L. Melo,

  Affiliation Department of Microbiology, Immunology, and Parasitology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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• Priscila Silva,

  Affiliation Department of Microbiology, Immunology, and Parasitology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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• Manoela Tiago,

  Affiliation School of Pharmaceutical Sciences, University of São Paulo (USP), São Paulo, Brazil

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• Alisson L. Matsuo,

  Affiliation Department of Microbiology, Immunology, and Parasitology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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• Luiz Juliano,

  Affiliation Department of Biophysics, EPM-UNIFESP, São Paulo, Brazil

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• Maria A. Juliano,

  Affiliation Department of Biophysics, EPM-UNIFESP, São Paulo, Brazil

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• Adriana K. Carmona,

  Affiliation Department of Biophysics, EPM-UNIFESP, São Paulo, Brazil

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• Luiz R. Travassos,

  Affiliation Department of Microbiology, Immunology, and Parasitology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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• Elaine G. Rodrigues

  * E-mail: rodrigues.elaine@unifesp.br

  Affiliation Department of Microbiology, Immunology, and Parasitology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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