Structural Basis for the Immunomodulatory Function of Cysteine Protease Inhibitor from Human Roundworm Ascaris lumbricoides

Guoqiang Mei; Jianmei Dong; Zhaotao Li; Sanling Liu; Yunfeng Liu; Mingze Sun; Guiyun Liu; Zhong Su; Jinsong Liu

doi:10.1371/journal.pone.0096069

Loading metrics

Open Access

Peer-reviewed

Research Article

Structural Basis for the Immunomodulatory Function of Cysteine Protease Inhibitor from Human Roundworm Ascaris lumbricoides

Guoqiang Mei,

Affiliations State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, School of Life Sciences, University of Science and Technology of China, Hefei, China
⨯
Jianmei Dong,

Affiliations State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, School of Life Sciences, University of Science and Technology of China, Hefei, China
⨯
Zhaotao Li,

Affiliation State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
⨯
Sanling Liu,

Current address: High Magnetic Field Laboratory, Hefei Institutes of Physical Sciences, Chinese Academy of Sciences, Hefei, China

Affiliation State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
⨯
Yunfeng Liu,

Affiliation State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
⨯
Mingze Sun,

Affiliation State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
⨯
Guiyun Liu,

Affiliation State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
⨯
Zhong Su ,

* E-mail: liu_jinsong@gibh.ac.cn (JL); su_zhong@gibh.ac.cn (ZS)

Affiliation State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
⨯
Jinsong Liu

* E-mail: liu_jinsong@gibh.ac.cn (JL); su_zhong@gibh.ac.cn (ZS)

Affiliations State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, School of Life Sciences, University of Science and Technology of China, Hefei, China
⨯

Structural Basis for the Immunomodulatory Function of Cysteine Protease Inhibitor from Human Roundworm Ascaris lumbricoides

Guoqiang Mei,
Jianmei Dong,
Zhaotao Li,
Sanling Liu,
Yunfeng Liu,
Mingze Sun,
Guiyun Liu,
Zhong Su,
Jinsong Liu

Published: April 29, 2014
https://doi.org/10.1371/journal.pone.0096069

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Proteases
Is the Subject Area "Proteases" applicable to this article?

Thanks for your feedback.
Nematode infections
Is the Subject Area "Nematode infections" applicable to this article?

Thanks for your feedback.
Parasitic diseases
Is the Subject Area "Parasitic diseases" applicable to this article?

Thanks for your feedback.
Ascaris lumbricoides
Is the Subject Area "Ascaris lumbricoides" applicable to this article?

Thanks for your feedback.
Crystal structure
Is the Subject Area "Crystal structure" applicable to this article?

Thanks for your feedback.
Recombinant proteins
Is the Subject Area "Recombinant proteins" applicable to this article?

Thanks for your feedback.
Immune suppression
Is the Subject Area "Immune suppression" applicable to this article?

Thanks for your feedback.
Cysteine protease inhibitors
Is the Subject Area "Cysteine protease inhibitors" applicable to this article?

Thanks for your feedback.