Impact of Metformin on Endothelial Ischemia-Reperfusion Injury in Humans In Vivo: A Prospective Randomized Open, Blinded-Endpoint Study

• Saloua El Messaoudi,

  Affiliations Department of Pharmacology-Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands, Department of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands

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• Tim H. Schreuder,

  Affiliation Department of Physiology, Radboud University Medical Center, Nijmegen, The Netherlands

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• Roel D. Kengen,

  Affiliation Department of Pharmacology-Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands

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• Gerard A. Rongen,

  Affiliations Department of Pharmacology-Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands, Department of General Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

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• Petra H. van den Broek,

  Affiliation Department of Pharmacology-Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands

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• Dick H. J. Thijssen,

  Affiliations Department of Physiology, Radboud University Medical Center, Nijmegen, The Netherlands, Research Institute for Sports and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom

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• Niels P. Riksen

  * E-mail: N.Riksen@aig.umcn.nl

  Affiliations Department of Pharmacology-Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands, Department of General Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

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