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Open Access

Peer-reviewed

Research Article

Effects of siRNA on RET/PTC3 Junction Oncogene in Papillary Thyroid Carcinoma: From Molecular and Cellular Studies to Preclinical Investigations

Hafiz Muhammad Ali,

Affiliations Université Paris-Sud 11, Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses, UMR 8203, Villejuif, France, CNRS, Villejuif, Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses, UMR 8203, Villejuif, France, Gustave Roussy, Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses, UMR 8203, Villejuif, France
⨯
Giorgia Urbinati,

Affiliations Université Paris-Sud 11, Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses, UMR 8203, Villejuif, France, CNRS, Villejuif, Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses, UMR 8203, Villejuif, France, Gustave Roussy, Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses, UMR 8203, Villejuif, France
⨯
Hubert Chapuis,

Affiliation Institut Galien, UMR CNRS 8612, Université Paris-Sud 11, Faculté de pharmacie, Châtenay-Malabry, France
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Didier DesmaEle,

Affiliation Institut Galien, UMR CNRS 8612, Université Paris-Sud 11, Faculté de pharmacie, Châtenay-Malabry, France
⨯
Jean-Rémi Bertrand,

Affiliations Université Paris-Sud 11, Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses, UMR 8203, Villejuif, France, CNRS, Villejuif, Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses, UMR 8203, Villejuif, France, Gustave Roussy, Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses, UMR 8203, Villejuif, France
⨯
Patrick Couvreur,

Affiliation Institut Galien, UMR CNRS 8612, Université Paris-Sud 11, Faculté de pharmacie, Châtenay-Malabry, France
⨯
Liliane Massaad-Massade

* E-mail: liliane.massade@igr.fr

Affiliations Université Paris-Sud 11, Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses, UMR 8203, Villejuif, France, CNRS, Villejuif, Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses, UMR 8203, Villejuif, France, Gustave Roussy, Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses, UMR 8203, Villejuif, France
⨯

Effects of siRNA on RET/PTC3 Junction Oncogene in Papillary Thyroid Carcinoma: From Molecular and Cellular Studies to Preclinical Investigations

Hafiz Muhammad Ali,
Giorgia Urbinati,
Hubert Chapuis,
Didier DesmaEle,
Jean-Rémi Bertrand,
Patrick Couvreur,
Liliane Massaad-Massade

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Published: April 23, 2014
https://doi.org/10.1371/journal.pone.0095964

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Small interfering RNA
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Oncogenes
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Apoptosis
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Cancer treatment
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Thyroid carcinoma
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Cancers and neoplasms
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Transfection
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Protein expression
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