Interleukin-17 Retinotoxicity Is Prevented by Gene Transfer of a Soluble Interleukin-17 Receptor Acting as a Cytokine Blocker: Implications for Age-Related Macular Degeneration

• Daniel Ardeljan,

  Affiliations Immunopathology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Yujuan Wang,

  Affiliations Immunopathology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China

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• Stanley Park,

  Affiliations Immunopathology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

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• Defen Shen,

  Affiliation Immunopathology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Xi Kathy Chu,

  Affiliation Immunopathology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Cheng-Rong Yu,

  Affiliation Molecular Immunology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Mones Abu-Asab,

  Affiliation Histology Core, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Jingsheng Tuo,

  Affiliation Immunopathology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Charles G. Eberhart,

  Affiliation Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Timothy W. Olsen,

  Affiliation Department of Ophthalmology, Emory University, Atlanta, Georgia, United States of America

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• Robert F. Mullins,

  Affiliation Department of Ophthalmology and Visual Sciences, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America

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• Gary White,

  Affiliation Genzyme Corporation, Framingham, Massachusetts, United States of America

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• Sam Wadsworth,

  Affiliation Genzyme Corporation, Framingham, Massachusetts, United States of America

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• Abraham Scaria,

  Affiliation Genzyme Corporation, Framingham, Massachusetts, United States of America

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• Chi-Chao Chan

  * E-mail: chanc@nei.nih.gov

  Affiliation Immunopathology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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