Overrepresentation of Glutamate Signaling in Alzheimer's Disease: Network-Based Pathway Enrichment Using Meta-Analysis of Genome-Wide Association Studies

Eduardo Pérez-Palma; Bernabé I. Bustos; Camilo F. Villamán; Marcelo A. Alarcón; Miguel E. Avila; Giorgia D. Ugarte; Ariel E. Reyes; Carlos Opazo; Giancarlo V. De Ferrari; the Alzheimer's Disease Neuroimaging Initiative; the NIA-LOAD/NCRAD Family Study Group

doi:10.1371/journal.pone.0095413

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Peer-reviewed

Research Article

Overrepresentation of Glutamate Signaling in Alzheimer's Disease: Network-Based Pathway Enrichment Using Meta-Analysis of Genome-Wide Association Studies

Eduardo Pérez-Palma ,

Contributed equally to this work with: Eduardo Pérez-Palma, Bernabé I. Bustos

Affiliation Center for Biomedical Research and FONDAP Center for Genome Regulation, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago, Chile
⨯
Bernabé I. Bustos ,

Contributed equally to this work with: Eduardo Pérez-Palma, Bernabé I. Bustos

Affiliation Center for Biomedical Research and FONDAP Center for Genome Regulation, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago, Chile
⨯
Camilo F. Villamán,

Affiliation Center for Biomedical Research and FONDAP Center for Genome Regulation, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago, Chile
⨯
Marcelo A. Alarcón,

Affiliations Center for Biomedical Research and FONDAP Center for Genome Regulation, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago, Chile, Faculty of Biological Sciences, Universidad de Concepción, Concepción, Chile
⨯
Miguel E. Avila,

Affiliations Center for Biomedical Research and FONDAP Center for Genome Regulation, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago, Chile, Faculty of Biological Sciences, Universidad de Concepción, Concepción, Chile
⨯
Giorgia D. Ugarte,

Affiliation Center for Biomedical Research and FONDAP Center for Genome Regulation, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago, Chile
⨯
Ariel E. Reyes,

Affiliation Center for Biomedical Research and FONDAP Center for Genome Regulation, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago, Chile
⨯
Carlos Opazo,

Affiliation Oxidation Biology Laboratory, The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, Australia
⨯
Giancarlo V. De Ferrari ,

* E-mail: gdeferrari@unab.cl

Affiliation Center for Biomedical Research and FONDAP Center for Genome Regulation, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago, Chile
⨯
the Alzheimer's Disease Neuroimaging Initiative,
the NIA-LOAD/NCRAD Family Study Group

Overrepresentation of Glutamate Signaling in Alzheimer's Disease: Network-Based Pathway Enrichment Using Meta-Analysis of Genome-Wide Association Studies

Eduardo Pérez-Palma,
Bernabé I. Bustos,
Camilo F. Villamán,
Marcelo A. Alarcón,
Miguel E. Avila,
Giorgia D. Ugarte,
Ariel E. Reyes,
Carlos Opazo,
Giancarlo V. De Ferrari,
the Alzheimer's Disease Neuroimaging Initiative

Published: April 22, 2014
https://doi.org/10.1371/journal.pone.0095413

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