Augmented Osteogenic Responses in Human Aortic Valve Cells Exposed to oxLDL and TLR4 Agonist: A Mechanistic Role of Notch1 and NF-κB Interaction

Open Access

Peer-reviewed

Research Article

Qingchun Zeng,

Affiliations Department of Surgery, University of Colorado Denver, Aurora, Colorado, United States of America, Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China
⨯
Rui Song,

Affiliations Department of Surgery, University of Colorado Denver, Aurora, Colorado, United States of America, Department of Pathophysiology, Southern Medical University, Guangzhou, Guangdong, China
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Lihua Ao,

Affiliation Department of Surgery, University of Colorado Denver, Aurora, Colorado, United States of America
⨯
Dingli Xu,

Affiliation Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China
⨯
Neil Venardos,

Affiliation Department of Surgery, University of Colorado Denver, Aurora, Colorado, United States of America
⨯
David A. Fullerton,

Affiliation Department of Surgery, University of Colorado Denver, Aurora, Colorado, United States of America
⨯
Xianzhong Meng

* E-mail: xianzhong.meng@ucdenver.edu

Affiliation Department of Surgery, University of Colorado Denver, Aurora, Colorado, United States of America
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Transcription factors
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Aortic valve
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Phosphorylation
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Immunoblotting
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Toll-like receptors
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Enzyme-linked immunoassays
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Macrophages
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Small interfering RNA
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