Intra-Myocardial Injection of Both Growth Factors and Heart Derived Sca-1+/CD31− Cells Attenuates Post-MI LV Remodeling More Than Does Cell Transplantation Alone: Neither Intervention Enhances Functionally Significant Cardiomyocyte Regeneration

Open Access

Peer-reviewed

Research Article

Intra-Myocardial Injection of Both Growth Factors and Heart Derived Sca-1⁺/CD31⁻ Cells Attenuates Post-MI LV Remodeling More Than Does Cell Transplantation Alone: Neither Intervention Enhances Functionally Significant Cardiomyocyte Regeneration

Xiaohong Wang ,

* E-mail: wangx270@umn.edu (XW); zhang047@umn.edu (JZ)

Affiliation Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America
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Qinglu Li,

Affiliation Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America
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Qingsong Hu,

Affiliation Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America
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Piradeep Suntharalingam,

Affiliation Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America
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Arthur H. L. From,

Affiliation Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America
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Jianyi Zhang

* E-mail: wangx270@umn.edu (XW); zhang047@umn.edu (JZ)

Affiliation Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America
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Myocardial infarction
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Cardiomyocytes
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Cell transplantation
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Heart
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Apoptosis
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Cell staining
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Cardiac transplantation
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Cell differentiation
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