MiR-330-Mediated Regulation of SH3GL2 Expression Enhances Malignant Behaviors of Glioblastoma Stem Cells by Activating ERK and PI3K/AKT Signaling Pathways

Yilong Yao; Yixue Xue; Jun Ma; Chao Shang; Ping Wang; Libo Liu; Wenjing Liu; Zhen Li; Shengtao Qu; Zhiqing Li; Yunhui Liu

doi:10.1371/journal.pone.0095060

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Open Access

Peer-reviewed

Research Article

MiR-330-Mediated Regulation of SH3GL2 Expression Enhances Malignant Behaviors of Glioblastoma Stem Cells by Activating ERK and PI3K/AKT Signaling Pathways

Yilong Yao,

Affiliation Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, People’s Republic of China
⨯
Yixue Xue,

Affiliations Department of Neurobiology, College of Basic Medicine, China Medical University, Shenyang, Liaoning Province, People’s Republic of China, Institute of Pathology and Pathophysiology, China Medical University, Shenyang, Liaoning Province, People’s Republic of China
⨯
Jun Ma,

Affiliations Department of Neurobiology, College of Basic Medicine, China Medical University, Shenyang, Liaoning Province, People’s Republic of China, Institute of Pathology and Pathophysiology, China Medical University, Shenyang, Liaoning Province, People’s Republic of China
⨯
Chao Shang,

Affiliations Department of Neurobiology, College of Basic Medicine, China Medical University, Shenyang, Liaoning Province, People’s Republic of China, Institute of Pathology and Pathophysiology, China Medical University, Shenyang, Liaoning Province, People’s Republic of China
⨯
Ping Wang,

Affiliations Department of Neurobiology, College of Basic Medicine, China Medical University, Shenyang, Liaoning Province, People’s Republic of China, Institute of Pathology and Pathophysiology, China Medical University, Shenyang, Liaoning Province, People’s Republic of China
⨯
Libo Liu,

Affiliations Department of Neurobiology, College of Basic Medicine, China Medical University, Shenyang, Liaoning Province, People’s Republic of China, Institute of Pathology and Pathophysiology, China Medical University, Shenyang, Liaoning Province, People’s Republic of China
⨯
Wenjing Liu,

Affiliation Department of Neurology, The First Affiliated Hospital, China Medical University, Shenyang, Liaoning Province, People’s Republic of China
⨯
Zhen Li,

Affiliation Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, People’s Republic of China
⨯
Shengtao Qu,

Affiliation Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, People’s Republic of China
⨯
Zhiqing Li,

Affiliation Department of Neurobiology, College of Basic Medicine, China Medical University, Shenyang, Liaoning Province, People’s Republic of China
⨯
Yunhui Liu

* E-mail: liuyh@sj-hospital.org

Affiliation Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, People’s Republic of China
⨯

MiR-330-Mediated Regulation of SH3GL2 Expression Enhances Malignant Behaviors of Glioblastoma Stem Cells by Activating ERK and PI3K/AKT Signaling Pathways

Yilong Yao,
Yixue Xue,
Jun Ma,
Chao Shang,
Ping Wang,
Libo Liu,
Wenjing Liu,
Zhen Li,
Shengtao Qu,
Zhiqing Li

Published: April 15, 2014
https://doi.org/10.1371/journal.pone.0095060

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