Patients with Tuberculosis Disease Have Mycobacterium tuberculosis-Specific CD8 T Cells with a Pro-Apoptotic Phenotype and Impaired Proliferative Capacity, Which Is Not Restored following Treatment

• Cheryl L. Day ,

  * E-mail: cheryl.day@emory.edu

  Affiliations South African Tuberculosis Vaccine Initiative (SATVI) and School of Child and Adolescent Health, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Observatory, South Africa, Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America, Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America, Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America

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• Noella D. Moshi,

  Affiliation South African Tuberculosis Vaccine Initiative (SATVI) and School of Child and Adolescent Health, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Observatory, South Africa

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• Deborah A. Abrahams,

  Affiliation South African Tuberculosis Vaccine Initiative (SATVI) and School of Child and Adolescent Health, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Observatory, South Africa

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• Michele van Rooyen,

  Affiliation South African Tuberculosis Vaccine Initiative (SATVI) and School of Child and Adolescent Health, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Observatory, South Africa

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• Terrence O'rie,

  Affiliation South African Tuberculosis Vaccine Initiative (SATVI) and School of Child and Adolescent Health, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Observatory, South Africa

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• Marwou de Kock,

  Affiliation South African Tuberculosis Vaccine Initiative (SATVI) and School of Child and Adolescent Health, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Observatory, South Africa

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• Willem A. Hanekom

  Affiliation South African Tuberculosis Vaccine Initiative (SATVI) and School of Child and Adolescent Health, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Observatory, South Africa

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