Tissue Inhibitor of Metalloproteinase-3 Knockout Mice Exhibit Enhanced Energy Expenditure through Thermogenesis

Yohsuke Hanaoka; Osamu Yasuda; Hirofumi Soejima; Keishi Miyata; Eiichiro Yamamoto; Yasuhiro Izumiya; Nobuyo Maeda; Mitsuru Ohishi; Hiromi Rakugi; Yuichi Oike; Shokei Kim-Mitsuyama; Hisao Ogawa

doi:10.1371/journal.pone.0094930

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Open Access

Peer-reviewed

Research Article

Tissue Inhibitor of Metalloproteinase-3 Knockout Mice Exhibit Enhanced Energy Expenditure through Thermogenesis

Yohsuke Hanaoka,

Affiliation Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
⨯
Osamu Yasuda ,

* E-mail: o-yasuda@kumamoto-u.ac.jp

Affiliation Department of Cardiovascular Clinical and Translational Research, Kumamoto University Hospital, Kumamoto University, Kumamoto, Japan
⨯
Hirofumi Soejima,

Affiliation Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
⨯
Keishi Miyata,

Affiliation Department of Molecular Genetics, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
⨯
Eiichiro Yamamoto,

Affiliation Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
⨯
Yasuhiro Izumiya,

Affiliation Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
⨯
Nobuyo Maeda,

Affiliation Department of Pathology and Laboratory Medicine, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
⨯
Mitsuru Ohishi,

Affiliation Department of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Science, Kagoshima University, Kagoshima, Japan
⨯
Hiromi Rakugi,

Affiliation Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Japan
⨯
Yuichi Oike,

Affiliation Department of Molecular Genetics, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
⨯
Shokei Kim-Mitsuyama,

Affiliation Department of Pharmacology and Molecular Therapeutics, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
⨯
Hisao Ogawa

Affiliation Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
⨯

Tissue Inhibitor of Metalloproteinase-3 Knockout Mice Exhibit Enhanced Energy Expenditure through Thermogenesis

Yohsuke Hanaoka,
Osamu Yasuda,
Hirofumi Soejima,
Keishi Miyata,
Eiichiro Yamamoto,
Yasuhiro Izumiya,
Nobuyo Maeda,
Mitsuru Ohishi,
Hiromi Rakugi,
Yuichi Oike

Published: April 15, 2014
https://doi.org/10.1371/journal.pone.0094930

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