Profiles of Extracellular miRNA in Cerebrospinal Fluid and Serum from Patients with Alzheimer's and Parkinson's Diseases Correlate with Disease Status and Features of Pathology

Kasandra Burgos; Ivana Malenica; Raghu Metpally; Amanda Courtright; Benjamin Rakela; Thomas Beach; Holly Shill; Charles Adler; Marwan Sabbagh; Stephen Villa; Waibhav Tembe; David Craig; Kendall Van Keuren-Jensen

doi:10.1371/journal.pone.0094839

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Open Access

Peer-reviewed

Research Article

Profiles of Extracellular miRNA in Cerebrospinal Fluid and Serum from Patients with Alzheimer's and Parkinson's Diseases Correlate with Disease Status and Features of Pathology

Kasandra Burgos ,

Contributed equally to this work with: Kasandra Burgos, Ivana Malenica

Affiliation Neurogenomics, Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America
⨯
Ivana Malenica ,

Contributed equally to this work with: Kasandra Burgos, Ivana Malenica

Affiliation Neurogenomics, Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America
⨯
Raghu Metpally,

Affiliation Neurogenomics, Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America
⨯
Amanda Courtright,

Affiliation Neurogenomics, Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America
⨯
Benjamin Rakela,

Affiliation Neurogenomics, Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America
⨯
Thomas Beach,

Affiliation Neurology, Banner Sun Health Research Institute, Sun City, Arizona, United States of America
⨯
Holly Shill,

Affiliation Neurology, Banner Sun Health Research Institute, Sun City, Arizona, United States of America
⨯
Charles Adler,

Affiliation Neurology, Mayo Clinic, Scottsdale, Arizona, United States of America
⨯
Marwan Sabbagh,

Affiliation Neurology, Banner Sun Health Research Institute, Sun City, Arizona, United States of America
⨯
Stephen Villa,

Affiliation Neurogenomics, Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America
⨯
Waibhav Tembe,

Affiliation Neurogenomics, Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America
⨯
David Craig,

Affiliation Neurogenomics, Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America
⨯
Kendall Van Keuren-Jensen

* E-mail: kjensen@tgen.org

Affiliation Neurogenomics, Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America
⨯

Profiles of Extracellular miRNA in Cerebrospinal Fluid and Serum from Patients with Alzheimer's and Parkinson's Diseases Correlate with Disease Status and Features of Pathology

Kasandra Burgos,
Ivana Malenica,
Raghu Metpally,
Amanda Courtright,
Benjamin Rakela,
Thomas Beach,
Holly Shill,
Charles Adler,
Marwan Sabbagh,
Stephen Villa

Published: May 5, 2014
https://doi.org/10.1371/journal.pone.0094839

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MicroRNAs
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Cerebrospinal fluid
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Parkinson disease
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Alzheimer's disease
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RNA sequencing
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