Metabolic Profiling of Dividing Cells in Live Rodent Brain by Proton Magnetic Resonance Spectroscopy (1HMRS) and LCModel Analysis

June-Hee Park; Hedok Lee; Rany Makaryus; Mei Yu; S. David Smith; Kasim Sayed; Tian Feng; Eric Holland; Annemie Van der Linden; Tom G. Bolwig; Grigori Enikolopov; Helene Benveniste

doi:10.1371/journal.pone.0094755

Loading metrics

Open Access

Peer-reviewed

Research Article

Metabolic Profiling of Dividing Cells in Live Rodent Brain by Proton Magnetic Resonance Spectroscopy (¹HMRS) and LCModel Analysis

June-Hee Park,

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America
⨯
Hedok Lee,

Affiliation Department of Anesthesiology, Stony Brook Medicine, Stony Brook, New York, United States of America
⨯
Rany Makaryus,

Affiliation Department of Anesthesiology, Stony Brook Medicine, Stony Brook, New York, United States of America
⨯
Mei Yu,

Affiliation Department of Anesthesiology, Stony Brook Medicine, Stony Brook, New York, United States of America
⨯
S. David Smith,

Affiliation Department of Anesthesiology, Stony Brook Medicine, Stony Brook, New York, United States of America
⨯
Kasim Sayed,

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America
⨯
Tian Feng,

Affiliation Department of Applied Mathematics and Statistics, Stony Brook University, New York, United States of America
⨯
Eric Holland,

Affiliation Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Annemie Van der Linden,

Affiliation Department of Biomedical Sciences, Bio-Imaging Laboratory, University of Antwerp, Belgium
⨯
Tom G. Bolwig,

Affiliation Neuropsychiatry Laboratory, Copenhagen University Hospital, Copenhagen, Denmark
⨯
Grigori Enikolopov,

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America
⨯
Helene Benveniste

* E-mail: helene.benveniste@stonybrookmedicine.edu

Affiliations Department of Anesthesiology, Stony Brook Medicine, Stony Brook, New York, United States of America, Department of Radiology, Stony Brook Medicine, Stony Brook, New York, United States of America
⨯

Metabolic Profiling of Dividing Cells in Live Rodent Brain by Proton Magnetic Resonance Spectroscopy (¹HMRS) and LCModel Analysis

June-Hee Park,
Hedok Lee,
Rany Makaryus,
Mei Yu,
S. David Smith,
Kasim Sayed,
Tian Feng,
Eric Holland,
Annemie Van der Linden,
Tom G. Bolwig

Published: May 12, 2014
https://doi.org/10.1371/journal.pone.0094755

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Lipids
Is the Subject Area "Lipids" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Hippocampus
Is the Subject Area "Hippocampus" applicable to this article?

Thanks for your feedback.
Metabolites
Is the Subject Area "Metabolites" applicable to this article?

Thanks for your feedback.
Lipid signaling
Is the Subject Area "Lipid signaling" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Magnetic resonance imaging
Is the Subject Area "Magnetic resonance imaging" applicable to this article?

Thanks for your feedback.