Chymase Mediates Injury and Mitochondrial Damage in Cardiomyocytes during Acute Ischemia/Reperfusion in the Dog

• Junying Zheng ,

  Contributed equally to this work with: Junying Zheng, Chih-Chang Wei

  Affiliation Birmingham Veteran Affairs Medical Center and Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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• Chih-Chang Wei ,

  Contributed equally to this work with: Junying Zheng, Chih-Chang Wei

  Affiliation Birmingham Veteran Affairs Medical Center and Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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• Naoki Hase,

  Affiliation Teijin Institute for Bio-Medical Research, Teijin Pharma Ltd, Tokyo, Japan

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• Ke Shi,

  Affiliation Birmingham Veteran Affairs Medical Center and Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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• Cheryl R. Killingsworth,

  Affiliation Birmingham Veteran Affairs Medical Center and Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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• Silvio H. Litovsky,

  Affiliation Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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• Pamela C. Powell,

  Affiliation Birmingham Veteran Affairs Medical Center and Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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• Tsunefumi Kobayashi,

  Affiliation Teijin Institute for Bio-Medical Research, Teijin Pharma Ltd, Tokyo, Japan

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• Carlos M. Ferrario,

  Affiliation Wake Forest University, Winston Salem, North Carolina, United States of America

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• Andras Rab,

  Affiliation Department of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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• Inmaculada Aban,

  Affiliation Department of Biostatistics University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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• James F. Collawn,

  Affiliation Department of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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• Louis J. Dell'Italia

  * E-mail: Louis.Dellitalia@va.gov

  Affiliation Birmingham Veteran Affairs Medical Center and Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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