miR-34a Modulates Angiotensin II-Induced Myocardial Hypertrophy by Direct Inhibition of ATG9A Expression and Autophagic Activity

Jionghua Huang; Wen Sun; He Huang; Jing Ye; Wei Pan; Yun Zhong; Chuanfang Cheng; Xiangyu You; Benrong Liu; Longgen Xiong; Shiming Liu

doi:10.1371/journal.pone.0094382

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Open Access

Peer-reviewed

Research Article

miR-34a Modulates Angiotensin II-Induced Myocardial Hypertrophy by Direct Inhibition of ATG9A Expression and Autophagic Activity

Jionghua Huang ,

Contributed equally to this work with: Jionghua Huang, Wen Sun

Affiliation Department of Cardiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Cardiovascular Disease, Guangzhou, China
⨯
Wen Sun ,

Contributed equally to this work with: Jionghua Huang, Wen Sun

Affiliation Department of Cardiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Cardiovascular Disease, Guangzhou, China
⨯
He Huang,

Affiliation Department of Cardiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Cardiovascular Disease, Guangzhou, China
⨯
Jing Ye,

Affiliation Department of Cardiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Cardiovascular Disease, Guangzhou, China
⨯
Wei Pan,

Affiliation Department of Cardiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Cardiovascular Disease, Guangzhou, China
⨯
Yun Zhong,

Affiliation Department of Cardiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Cardiovascular Disease, Guangzhou, China
⨯
Chuanfang Cheng,

Affiliation Department of Cardiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Cardiovascular Disease, Guangzhou, China
⨯
Xiangyu You,

Affiliation Department of Cardiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Cardiovascular Disease, Guangzhou, China
⨯
Benrong Liu,

Affiliation Department of Cardiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Cardiovascular Disease, Guangzhou, China
⨯
Longgen Xiong ,

* E-mail: xionglg66@126.com (LX); gzliushiming@126.com (SL)

Affiliation Department of Cardiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Cardiovascular Disease, Guangzhou, China
⨯
Shiming Liu

* E-mail: xionglg66@126.com (LX); gzliushiming@126.com (SL)

Affiliation Department of Cardiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Cardiovascular Disease, Guangzhou, China
⨯

miR-34a Modulates Angiotensin II-Induced Myocardial Hypertrophy by Direct Inhibition of ATG9A Expression and Autophagic Activity

Jionghua Huang,
Wen Sun,
He Huang,
Jing Ye,
Wei Pan,
Yun Zhong,
Chuanfang Cheng,
Xiangyu You,
Benrong Liu,
Longgen Xiong

Published: April 11, 2014
https://doi.org/10.1371/journal.pone.0094382

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Cardiomyocytes
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Cardiac hypertrophy
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Autophagic cell death
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Gene expression
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