A Three Step Network Based Approach (TSNBA) to Finding Disease Molecular Signature and Key Regulators: A Case Study of IL-1 and TNF-Alpha Stimulated Inflammation

Open Access

Peer-reviewed

Research Article

Jihong Yang ,

Contributed equally to this work with: Jihong Yang, Zheng Li

Affiliation Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
⨯
Zheng Li ,

Contributed equally to this work with: Jihong Yang, Zheng Li

* E-mail: lizheng1@gmail.com (ZL); fanxh@zju.edu.cn (XF)

Affiliation State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China
⨯
Xiaohui Fan ,

* E-mail: lizheng1@gmail.com (ZL); fanxh@zju.edu.cn (XF)

Affiliation Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
⨯
Yiyu Cheng

Affiliation Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
⨯

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Inflammation
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Regulator genes
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Genetic networks
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Gene expression
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Gene regulation
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Transcription factors
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Gene prediction
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Molecular pathology
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