Inhibition of Fatty Acid Binding Proteins Elevates Brain Anandamide Levels and Produces Analgesia

Martin Kaczocha; Mario J. Rebecchi; Brian P. Ralph; Yu-Han Gary Teng; William T. Berger; William Galbavy; Matthew W. Elmes; Sherrye T. Glaser; Liqun Wang; Robert C. Rizzo; Dale G. Deutsch; Iwao Ojima

doi:10.1371/journal.pone.0094200

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Open Access

Peer-reviewed

Research Article

Inhibition of Fatty Acid Binding Proteins Elevates Brain Anandamide Levels and Produces Analgesia

Martin Kaczocha ,

* E-mail: Martin.Kaczocha@Stonybrook.edu

Affiliation Department of Anesthesiology, Stony Brook University, Stony Brook, New York, United States of America
⨯
Mario J. Rebecchi,

Affiliation Department of Anesthesiology, Stony Brook University, Stony Brook, New York, United States of America
⨯
Brian P. Ralph,

Affiliation Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, United States of America
⨯
Yu-Han Gary Teng,

Affiliation Department of Chemistry and the Institute of Chemical Biology and Drug Discovery, Stony Brook University, Stony Brook, New York, United States of America
⨯
William T. Berger,

Affiliation Department of Chemistry and the Institute of Chemical Biology and Drug Discovery, Stony Brook University, Stony Brook, New York, United States of America
⨯
William Galbavy,

Affiliation Department of Anesthesiology, Stony Brook University, Stony Brook, New York, United States of America
⨯
Matthew W. Elmes,

Affiliation Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, United States of America
⨯
Sherrye T. Glaser,

Affiliation Department of Biological Sciences, Kingsborough Community College, Brooklyn, New York, United States of America
⨯
Liqun Wang,

Affiliation Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, United States of America
⨯
Robert C. Rizzo,

Affiliation Department of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, New York, United States of America
⨯
Dale G. Deutsch,

Affiliation Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, United States of America
⨯
Iwao Ojima

Affiliation Department of Chemistry and the Institute of Chemical Biology and Drug Discovery, Stony Brook University, Stony Brook, New York, United States of America
⨯

Inhibition of Fatty Acid Binding Proteins Elevates Brain Anandamide Levels and Produces Analgesia

Martin Kaczocha,
Mario J. Rebecchi,
Brian P. Ralph,
Yu-Han Gary Teng,
William T. Berger,
William Galbavy,
Matthew W. Elmes,
Sherrye T. Glaser,
Liqun Wang,
Robert C. Rizzo

Published: April 4, 2014
https://doi.org/10.1371/journal.pone.0094200

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