Regional-Specific Effects of Ovarian Hormone Loss on Synaptic Plasticity in Adult Human APOE Targeted Replacement Mice

Rebecca C. Klein; Shyla Saini; M-Louise Risher; Shawn K. Acheson; Rebekah L. Fleming; Hannah G. Sexton; H. Scott Swartzwelder; Scott D. Moore

doi:10.1371/journal.pone.0094071

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Peer-reviewed

Research Article

Regional-Specific Effects of Ovarian Hormone Loss on Synaptic Plasticity in Adult Human APOE Targeted Replacement Mice

Rebecca C. Klein ,

* E-mail: rck11@duke.edu

Affiliations Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America, MIRECC, Durham Veterans Affairs Medical Center, Durham, North Carolina, United States of America
⨯
Shyla Saini,

Affiliation Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
M-Louise Risher,

Affiliation Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Shawn K. Acheson,

Affiliations Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America, Neurobiology Research Lab, Durham Veterans Affairs Medical Center, Durham, North Carolina, United States of America
⨯
Rebekah L. Fleming,

Affiliations Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America, Neurobiology Research Lab, Durham Veterans Affairs Medical Center, Durham, North Carolina, United States of America
⨯
Hannah G. Sexton,

Affiliations Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America, Neurobiology Research Lab, Durham Veterans Affairs Medical Center, Durham, North Carolina, United States of America
⨯
H. Scott Swartzwelder,

Affiliations Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America, Neurobiology Research Lab, Durham Veterans Affairs Medical Center, Durham, North Carolina, United States of America
⨯
Scott D. Moore

Affiliations Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, United States of America, MIRECC, Durham Veterans Affairs Medical Center, Durham, North Carolina, United States of America
⨯

Regional-Specific Effects of Ovarian Hormone Loss on Synaptic Plasticity in Adult Human APOE Targeted Replacement Mice

Rebecca C. Klein,
Shyla Saini,
M-Louise Risher,
Shawn K. Acheson,
Rebekah L. Fleming,
Hannah G. Sexton,
H. Scott Swartzwelder,
Scott D. Moore

Published: April 14, 2014
https://doi.org/10.1371/journal.pone.0094071

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