Minocycline and Risperidone Prevent Microglia Activation and Rescue Behavioral Deficits Induced by Neonatal Intrahippocampal Injection of Lipopolysaccharide in Rats

Furong Zhu; Yingjun Zheng; Yu-qiang Ding; Yong Liu; Xianghui Zhang; Renrong Wu; Xiaofeng Guo; Jingping Zhao

doi:10.1371/journal.pone.0093966

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Research Article

Minocycline and Risperidone Prevent Microglia Activation and Rescue Behavioral Deficits Induced by Neonatal Intrahippocampal Injection of Lipopolysaccharide in Rats

Furong Zhu ,

Contributed equally to this work with: Furong Zhu, Yingjun Zheng

Affiliation Mental Health Institute of The Second Xiangya Hospital, National Technology Institute of Psychiatry, Key Laboratory of Psychiatry and Mental Health of Hunan Province, Central South University, Changsha, Hunan, China
⨯
Yingjun Zheng ,

Contributed equally to this work with: Furong Zhu, Yingjun Zheng

Affiliations Mental Health Institute of The Second Xiangya Hospital, National Technology Institute of Psychiatry, Key Laboratory of Psychiatry and Mental Health of Hunan Province, Central South University, Changsha, Hunan, China, Department of General Psychiatry, Guangzhou Brain Hospital, Affiliated Hospital of Guangzhou Medical College, Guangzhou, Guangdong, China
⨯
Yu-qiang Ding,

Affiliations Mental Health Institute of The Second Xiangya Hospital, National Technology Institute of Psychiatry, Key Laboratory of Psychiatry and Mental Health of Hunan Province, Central South University, Changsha, Hunan, China, Department of Anatomy and Neurobiology, Tongji University School of Medicine, Shanghai, China
⨯
Yong Liu,

Affiliation Mental Health Institute of The Second Xiangya Hospital, National Technology Institute of Psychiatry, Key Laboratory of Psychiatry and Mental Health of Hunan Province, Central South University, Changsha, Hunan, China
⨯
Xianghui Zhang,

Affiliation Mental Health Institute of The Second Xiangya Hospital, National Technology Institute of Psychiatry, Key Laboratory of Psychiatry and Mental Health of Hunan Province, Central South University, Changsha, Hunan, China
⨯
Renrong Wu,

Affiliation Mental Health Institute of The Second Xiangya Hospital, National Technology Institute of Psychiatry, Key Laboratory of Psychiatry and Mental Health of Hunan Province, Central South University, Changsha, Hunan, China
⨯
Xiaofeng Guo,

Affiliation Mental Health Institute of The Second Xiangya Hospital, National Technology Institute of Psychiatry, Key Laboratory of Psychiatry and Mental Health of Hunan Province, Central South University, Changsha, Hunan, China
⨯
Jingping Zhao

* E-mail: zhaojingpingcsu@163.com

Affiliation Mental Health Institute of The Second Xiangya Hospital, National Technology Institute of Psychiatry, Key Laboratory of Psychiatry and Mental Health of Hunan Province, Central South University, Changsha, Hunan, China
⨯

Minocycline and Risperidone Prevent Microglia Activation and Rescue Behavioral Deficits Induced by Neonatal Intrahippocampal Injection of Lipopolysaccharide in Rats

Furong Zhu,
Yingjun Zheng,
Yu-qiang Ding,
Yong Liu,
Xianghui Zhang,
Renrong Wu,
Xiaofeng Guo,
Jingping Zhao

Published: April 4, 2014
https://doi.org/10.1371/journal.pone.0093966

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Rats
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