Gonadotropin-Releasing Hormone Agonists Sensitize, and Resensitize, Prostate Cancer Cells to Docetaxel in a p53-Dependent Manner

Open Access

Peer-reviewed

Research Article

Roberta M. Moretti,

Affiliation Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milano, Italy
⨯
Marina Montagnani Marelli,

Affiliation Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milano, Italy
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Deanne M. Taylor,

Affiliation Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Reproductive Sciences, UMDNJ-Robert Wood Johnson Medical School, Morristown, New Jersey, United States of America
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Paolo G. V. Martini,

Affiliation Drug Discovery and Translational Research, Shire Rare Diseases Unit, Lexington, Massachusetts, United States of America
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Monica Marzagalli,

Affiliation Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milano, Italy
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Patrizia Limonta

* E-mail: patrizia.limonta@unimi.it

Affiliation Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milano, Italy
⨯

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Prostate cancer
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DU145 cells
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Cancer treatment
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Apoptosis
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Phosphorylation
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Gene expression
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MAPK signaling cascades
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Drug therapy
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