Autosomal Recessive Transmission of a Rare KRT74 Variant Causes Hair and Nail Ectodermal Dysplasia: Allelism with Dominant Woolly Hair/Hypotrichosis

Doroteya Raykova; Joakim Klar; Aysha Azhar; Tahir Naeem Khan; Naveed Altaf Malik; Muhammad Iqbal; Muhammad Tariq; Shahid Mahmood Baig; Niklas Dahl

doi:10.1371/journal.pone.0093607

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Open Access

Peer-reviewed

Research Article

Autosomal Recessive Transmission of a Rare KRT74 Variant Causes Hair and Nail Ectodermal Dysplasia: Allelism with Dominant Woolly Hair/Hypotrichosis

Doroteya Raykova,

Affiliation Department of Immunology, Genetics and Pathology, Science for Life Laboratory at Uppsala University, Biomedical Center, Uppsala, Sweden
⨯
Joakim Klar,

Affiliation Department of Immunology, Genetics and Pathology, Science for Life Laboratory at Uppsala University, Biomedical Center, Uppsala, Sweden
⨯
Aysha Azhar,

Affiliation Human Molecular Genetics Laboratory, Health Biotechnology Division, National Institute for Biotechnology and Genetic Engineering, Faisalabad, Pakistan
⨯
Tahir Naeem Khan,

Affiliation Human Molecular Genetics Laboratory, Health Biotechnology Division, National Institute for Biotechnology and Genetic Engineering, Faisalabad, Pakistan
⨯
Naveed Altaf Malik,

Affiliation Human Molecular Genetics Laboratory, Health Biotechnology Division, National Institute for Biotechnology and Genetic Engineering, Faisalabad, Pakistan
⨯
Muhammad Iqbal,

Affiliation Department of Nuclear Medicine, Punjab Institute of Nuclear Medicines Hospital, Faisalabad, Pakistan
⨯
Muhammad Tariq,

Affiliation Human Molecular Genetics Laboratory, Health Biotechnology Division, National Institute for Biotechnology and Genetic Engineering, Faisalabad, Pakistan
⨯
Shahid Mahmood Baig,

Affiliation Human Molecular Genetics Laboratory, Health Biotechnology Division, National Institute for Biotechnology and Genetic Engineering, Faisalabad, Pakistan
⨯
Niklas Dahl

* E-mail: Niklas.Dahl@igp.uu.se

Affiliation Department of Immunology, Genetics and Pathology, Science for Life Laboratory at Uppsala University, Biomedical Center, Uppsala, Sweden
⨯

Autosomal Recessive Transmission of a Rare KRT74 Variant Causes Hair and Nail Ectodermal Dysplasia: Allelism with Dominant Woolly Hair/Hypotrichosis

Doroteya Raykova,
Joakim Klar,
Aysha Azhar,
Tahir Naeem Khan,
Naveed Altaf Malik,
Muhammad Iqbal,
Muhammad Tariq,
Shahid Mahmood Baig,
Niklas Dahl

Published: April 8, 2014
https://doi.org/10.1371/journal.pone.0093607

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