The Dimerization Domain in DapE Enzymes Is required for Catalysis

Boguslaw Nocek; Anna Starus; Magdalena Makowska-Grzyska; Blanca Gutierrez; Stephen Sanchez; Robert Jedrzejczak; Jamey C. Mack; Kenneth W. Olsen; Andrzej Joachimiak; Richard C. Holz

doi:10.1371/journal.pone.0093593

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Peer-reviewed

Research Article

The Dimerization Domain in DapE Enzymes Is required for Catalysis

Boguslaw Nocek,

Affiliation Center for Structural Genomics of Infectious Diseases, Computation Institute, University of Chicago, Chicago, Illinois, United States of America
⨯
Anna Starus,

Affiliation The Department of Chemistry and Biochemistry, Loyola University-Chicago, Chicago, Illinois, United States of America
⨯
Magdalena Makowska-Grzyska,

Affiliation Center for Structural Genomics of Infectious Diseases, Computation Institute, University of Chicago, Chicago, Illinois, United States of America
⨯
Blanca Gutierrez,

Affiliation The Department of Chemistry and Biochemistry, Loyola University-Chicago, Chicago, Illinois, United States of America
⨯
Stephen Sanchez,

Affiliation The Department of Chemistry and Biochemistry, Loyola University-Chicago, Chicago, Illinois, United States of America
⨯
Robert Jedrzejczak,

Affiliation The Midwest Center for Structural Genomics, Bioscience Division, Argonne National Laboratory, Lemont, Illinois, United States of America
⨯
Jamey C. Mack,

Affiliation The Midwest Center for Structural Genomics, Bioscience Division, Argonne National Laboratory, Lemont, Illinois, United States of America
⨯
Kenneth W. Olsen,

Affiliation The Department of Chemistry and Biochemistry, Loyola University-Chicago, Chicago, Illinois, United States of America
⨯
Andrzej Joachimiak ,

* E-mail: andrzejj@anl.gov (AJ); richard.holz@marquette.edu (RCH)

Affiliations Center for Structural Genomics of Infectious Diseases, Computation Institute, University of Chicago, Chicago, Illinois, United States of America, The Midwest Center for Structural Genomics, Bioscience Division, Argonne National Laboratory, Lemont, Illinois, United States of America
⨯
Richard C. Holz

* E-mail: andrzejj@anl.gov (AJ); richard.holz@marquette.edu (RCH)

Affiliation Department of Chemistry, Marquette University, Milwaukee, Wisconsin, United States of America
⨯

The Dimerization Domain in DapE Enzymes Is required for Catalysis

Boguslaw Nocek,
Anna Starus,
Magdalena Makowska-Grzyska,
Blanca Gutierrez,
Stephen Sanchez,
Robert Jedrzejczak,
Jamey C. Mack,
Kenneth W. Olsen,
Andrzej Joachimiak,
Richard C. Holz

Published: May 7, 2014
https://doi.org/10.1371/journal.pone.0093593

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