Positioning of APOBEC3G/F Mutational Hotspots in the Human Immunodeficiency Virus Genome Favors Reduced Recognition by CD8+ T Cells

Open Access

Peer-reviewed

Research Article

Positioning of APOBEC3G/F Mutational Hotspots in the Human Immunodeficiency Virus Genome Favors Reduced Recognition by CD8⁺ T Cells

Mahdis Monajemi,

Affiliation Immunology and Infectious Diseases Program, Division of Biomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, NL, Canada
⨯
Claire F. Woodworth,

Affiliation Immunology and Infectious Diseases Program, Division of Biomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, NL, Canada
⨯
Katrin Zipperlen,

Affiliation Immunology and Infectious Diseases Program, Division of Biomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, NL, Canada
⨯
Maureen Gallant,

Affiliation Immunology and Infectious Diseases Program, Division of Biomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, NL, Canada
⨯
Michael D. Grant ,

* E-mail: mgrant@mun.ca (MDG); mlarijani@mun.ca (ML)

Affiliation Immunology and Infectious Diseases Program, Division of Biomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, NL, Canada
⨯
Mani Larijani

* E-mail: mgrant@mun.ca (MDG); mlarijani@mun.ca (ML)

Affiliation Immunology and Infectious Diseases Program, Division of Biomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, NL, Canada
⨯

HIV
Is the Subject Area "HIV" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Cytotoxic T cells
Is the Subject Area "Cytotoxic T cells" applicable to this article?

Thanks for your feedback.
Microbial mutation
Is the Subject Area "Microbial mutation" applicable to this article?

Thanks for your feedback.
Mutation databases
Is the Subject Area "Mutation databases" applicable to this article?

Thanks for your feedback.
Genomics
Is the Subject Area "Genomics" applicable to this article?

Thanks for your feedback.
Viral genomics
Is the Subject Area "Viral genomics" applicable to this article?

Thanks for your feedback.
Viral genome
Is the Subject Area "Viral genome" applicable to this article?

Thanks for your feedback.