U4 at the 3′ UTR of PB1 Segment of H5N1 Influenza Virus Promotes RNA Polymerase Activity and Contributes to Viral Pathogenicity

Wei Sun; Jing Li; Pengfei Han; Yinhui Yang; Xiaoping Kang; Yuchang Li; Jiaming Li; Yu Zhang; Xiaoyan Wu; Tao Jiang; Chengfeng Qin; Yi Hu; Qingyu Zhu

doi:10.1371/journal.pone.0093366

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Open Access

Peer-reviewed

Research Article

U₄ at the 3′ UTR of PB1 Segment of H5N1 Influenza Virus Promotes RNA Polymerase Activity and Contributes to Viral Pathogenicity

Wei Sun ,

Contributed equally to this work with: Wei Sun, Jing Li

Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China
⨯
Jing Li ,

Contributed equally to this work with: Wei Sun, Jing Li

Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China
⨯
Pengfei Han,

Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China
⨯
Yinhui Yang,

Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China
⨯
Xiaoping Kang,

Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China
⨯
Yuchang Li,

Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China
⨯
Jiaming Li,

Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China
⨯
Yu Zhang,

Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China
⨯
Xiaoyan Wu,

Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China
⨯
Tao Jiang,

Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China
⨯
Chengfeng Qin,

Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China
⨯
Yi Hu ,

* E-mail: qingyzh@aliyun.com (QYZ); huyi-amms@163.com (YH)

Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China
⨯
Qingyu Zhu

* E-mail: qingyzh@aliyun.com (QYZ); huyi-amms@163.com (YH)

Affiliation State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China
⨯

U₄ at the 3′ UTR of PB1 Segment of H5N1 Influenza Virus Promotes RNA Polymerase Activity and Contributes to Viral Pathogenicity

Wei Sun,
Jing Li,
Pengfei Han,
Yinhui Yang,
Xiaoping Kang,
Yuchang Li,
Jiaming Li,
Yu Zhang,
Xiaoyan Wu,
Tao Jiang

Published: March 27, 2014
https://doi.org/10.1371/journal.pone.0093366

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