Krüppel Like Factor 4 Promoter Undergoes Active Demethylation during Monocyte/Macrophage Differentiation

Manjula Karpurapu; Ravi Ranjan; Jing Deng; Sangwoon Chung; Yong Gyu Lee; Lei Xiao; Teja Srinivas Nirujogi; Jeffrey R. Jacobson; Gye Young Park; John W Christman

doi:10.1371/journal.pone.0093362

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Peer-reviewed

Research Article

Krüppel Like Factor 4 Promoter Undergoes Active Demethylation during Monocyte/Macrophage Differentiation

Manjula Karpurapu,

Affiliation Section of Pulmonary, Allergy, Critical Care and Sleep Medicine, The Ohio State University Wexner Medical Center, Davis Heart and Lung Research Institute, Columbus, Ohio, United States of America
⨯
Ravi Ranjan,

Affiliation Section of Pulmonary, Critical Care, Sleep and Allergy, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Jing Deng,

Affiliation Section of Pulmonary, Allergy, Critical Care and Sleep Medicine, The Ohio State University Wexner Medical Center, Davis Heart and Lung Research Institute, Columbus, Ohio, United States of America
⨯
Sangwoon Chung,

Affiliation Section of Pulmonary, Allergy, Critical Care and Sleep Medicine, The Ohio State University Wexner Medical Center, Davis Heart and Lung Research Institute, Columbus, Ohio, United States of America
⨯
Yong Gyu Lee,

Affiliation Section of Pulmonary, Allergy, Critical Care and Sleep Medicine, The Ohio State University Wexner Medical Center, Davis Heart and Lung Research Institute, Columbus, Ohio, United States of America
⨯
Lei Xiao,

Affiliation Section of Pulmonary, Critical Care, Sleep and Allergy, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Teja Srinivas Nirujogi,

Affiliation Section of Pulmonary, Allergy, Critical Care and Sleep Medicine, The Ohio State University Wexner Medical Center, Davis Heart and Lung Research Institute, Columbus, Ohio, United States of America
⨯
Jeffrey R. Jacobson,

Affiliation Institute for Personalized Respiratory Medicine, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Gye Young Park,

Affiliation Section of Pulmonary, Critical Care, Sleep and Allergy, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
John W Christman

* E-mail: John.Christman@osumc.edu

Affiliation Section of Pulmonary, Allergy, Critical Care and Sleep Medicine, The Ohio State University Wexner Medical Center, Davis Heart and Lung Research Institute, Columbus, Ohio, United States of America
⨯

Krüppel Like Factor 4 Promoter Undergoes Active Demethylation during Monocyte/Macrophage Differentiation

Manjula Karpurapu,
Ravi Ranjan,
Jing Deng,
Sangwoon Chung,
Yong Gyu Lee,
Lei Xiao,
Teja Srinivas Nirujogi,
Jeffrey R. Jacobson,
Gye Young Park,
John W Christman

Published: April 2, 2014
https://doi.org/10.1371/journal.pone.0093362

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DNA methylation
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Cell differentiation
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Macrophages
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