Inhibition of Nerve Growth Factor-Induced Neurite Outgrowth from PC12 Cells by Dexamethasone: Signaling Pathways through the Glucocorticoid Receptor and Phosphorylated Akt and ERK1/2

Open Access

Peer-reviewed

Research Article

Kazuki Terada,

Affiliations Laboratory of Drug Design and Drug Delivery, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan, Laboratory of Clinical Pharmacology, Yokohama College of Pharmacy, Kanagawa, Japan
⨯
Yoshitsugu Kojima,

Affiliation Research and Development Department 2, Nippon Sigmax Co., Ltd., Tokyo, Japan
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Takayuki Watanabe,

Affiliation Research and Development Department 2, Nippon Sigmax Co., Ltd., Tokyo, Japan
⨯
Nobuo Izumo,

Affiliation Laboratory of Clinical Pharmacology, Yokohama College of Pharmacy, Kanagawa, Japan
⨯
Koji Chiba ,

* E-mail: k.chiba@hamayaku.ac.jp

Affiliation Laboratory of Clinical Pharmacology, Yokohama College of Pharmacy, Kanagawa, Japan
⨯
Yoshiharu Karube

Affiliation Laboratory of Drug Design and Drug Delivery, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan
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Neurites
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Neuronal differentiation
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Signal inhibition
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AKT signaling cascade
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Ras signaling
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Phosphorylation
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Cell signaling
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Central nervous system
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