Overexpression of S100A7 Protects LPS-Induced Mitochondrial Dysfunction and Stimulates IL-6 and IL-8 in HaCaT Cells

Wenyan Sun; Yan Zheng; Zhuoyang Lu; Yang Cui; Qiong Tian; Shengxiang Xiao; Feng Liu; Jiankang Liu

doi:10.1371/journal.pone.0092927

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Open Access

Peer-reviewed

Research Article

Overexpression of S100A7 Protects LPS-Induced Mitochondrial Dysfunction and Stimulates IL-6 and IL-8 in HaCaT Cells

Wenyan Sun,

Affiliation Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology and Frontier Institute of Science and Technology, Xi’an Jiaotong University, Xi’an, P. R. China
⨯
Yan Zheng ,

* E-mail: zenyan66@126.com

Affiliation Department of Dermatology, the 2nd Affiliated Hospital of Xi’an Jiaotong University, Xi’an, P. R. China
⨯
Zhuoyang Lu,

Affiliation Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology and Frontier Institute of Science and Technology, Xi’an Jiaotong University, Xi’an, P. R. China
⨯
Yang Cui,

Affiliation Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology and Frontier Institute of Science and Technology, Xi’an Jiaotong University, Xi’an, P. R. China
⨯
Qiong Tian,

Affiliation Department of Dermatology, the 2nd Affiliated Hospital of Xi’an Jiaotong University, Xi’an, P. R. China
⨯
Shengxiang Xiao,

Affiliation Department of Dermatology, the 2nd Affiliated Hospital of Xi’an Jiaotong University, Xi’an, P. R. China
⨯
Feng Liu,

Affiliations Department of Medicine, University of California Irvine Medical School, Irvine, United States of America, Chao Family Comprehensive Cancer Center, University of California Irvine Medical School, Irvine, United States of America
⨯
Jiankang Liu

Affiliations Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology and Frontier Institute of Science and Technology, Xi’an Jiaotong University, Xi’an, P. R. China, Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, United States of America
⨯

Overexpression of S100A7 Protects LPS-Induced Mitochondrial Dysfunction and Stimulates IL-6 and IL-8 in HaCaT Cells

Wenyan Sun,
Yan Zheng,
Zhuoyang Lu,
Yang Cui,
Qiong Tian,
Shengxiang Xiao,
Feng Liu,
Jiankang Liu

Published: March 26, 2014
https://doi.org/10.1371/journal.pone.0092927

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