Bovine Exome Sequence Analysis and Targeted SNP Genotyping of Recessive Fertility Defects BH1, HH2, and HH3 Reveal a Putative Causative Mutation in SMC2 for HH3

Matthew C. McClure; Derek Bickhart; Dan Null; Paul VanRaden; Lingyang Xu; George Wiggans; George Liu; Steve Schroeder; Jarret Glasscock; Jon Armstrong; John B. Cole; Curtis P. Van Tassell; Tad S. Sonstegard

doi:10.1371/journal.pone.0092769

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Peer-reviewed

Research Article

Bovine Exome Sequence Analysis and Targeted SNP Genotyping of Recessive Fertility Defects BH1, HH2, and HH3 Reveal a Putative Causative Mutation in SMC2 for HH3

Matthew C. McClure,

Affiliation United States Department of Agriculture, Agriculture Research Service, Bovine Functional Genomics Laboratory, Beltsville, Maryland, United States of America
⨯
Derek Bickhart,

Affiliation United States Department of Agriculture, Agriculture Research Service, Animal Improvement Programs Laboratory, Beltsville, Maryland, United States of America
⨯
Dan Null,

Affiliation United States Department of Agriculture, Agriculture Research Service, Animal Improvement Programs Laboratory, Beltsville, Maryland, United States of America
⨯
Paul VanRaden,

Affiliation United States Department of Agriculture, Agriculture Research Service, Animal Improvement Programs Laboratory, Beltsville, Maryland, United States of America
⨯
Lingyang Xu,

Affiliation United States Department of Agriculture, Agriculture Research Service, Bovine Functional Genomics Laboratory, Beltsville, Maryland, United States of America
⨯
George Wiggans,

Affiliation United States Department of Agriculture, Agriculture Research Service, Animal Improvement Programs Laboratory, Beltsville, Maryland, United States of America
⨯
George Liu,

Affiliation United States Department of Agriculture, Agriculture Research Service, Bovine Functional Genomics Laboratory, Beltsville, Maryland, United States of America
⨯
Steve Schroeder,

Affiliation United States Department of Agriculture, Agriculture Research Service, Bovine Functional Genomics Laboratory, Beltsville, Maryland, United States of America
⨯
Jarret Glasscock,

Affiliation Cofactor Genomics, St. Louis, Missouri, United States of America
⨯
Jon Armstrong,

Affiliation Cofactor Genomics, St. Louis, Missouri, United States of America
⨯
John B. Cole,

Affiliation United States Department of Agriculture, Agriculture Research Service, Animal Improvement Programs Laboratory, Beltsville, Maryland, United States of America
⨯
Curtis P. Van Tassell,

Affiliation United States Department of Agriculture, Agriculture Research Service, Bovine Functional Genomics Laboratory, Beltsville, Maryland, United States of America
⨯
Tad S. Sonstegard

* E-mail: Tad.sonstegard@ars.usda.gov

Affiliation United States Department of Agriculture, Agriculture Research Service, Bovine Functional Genomics Laboratory, Beltsville, Maryland, United States of America
⨯

Bovine Exome Sequence Analysis and Targeted SNP Genotyping of Recessive Fertility Defects BH1, HH2, and HH3 Reveal a Putative Causative Mutation in SMC2 for HH3

Matthew C. McClure,
Derek Bickhart,
Dan Null,
Paul VanRaden,
Lingyang Xu,
George Wiggans,
George Liu,
Steve Schroeder,
Jarret Glasscock,
Jon Armstrong

Published: March 25, 2014
https://doi.org/10.1371/journal.pone.0092769

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Single nucleotide polymorphisms
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