In Vivo Imaging of mGluR5 Changes during Epileptogenesis Using [11C]ABP688 PET in Pilocarpine-Induced Epilepsy Rat Model

Hongyoon Choi; Yu Kyeong Kim; So Won Oh; Hyung-Jun Im; Do Won Hwang; Hyejin Kang; Boeun Lee; Yun-Sang Lee; Jae Min Jeong; E. Edmund Kim; June-Key Chung; Dong Soo Lee

doi:10.1371/journal.pone.0092765

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Open Access

Peer-reviewed

Research Article

In Vivo Imaging of mGluR5 Changes during Epileptogenesis Using [¹¹C]ABP688 PET in Pilocarpine-Induced Epilepsy Rat Model

Hongyoon Choi,

Affiliations Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea, Department of Molecular Medicine and Biopharmaceutical Science, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea
⨯
Yu Kyeong Kim ,

* E-mail: dsl@plaza.snu.ac.kr (DSL); yk3181@snu.ac.kr (YKK)

Affiliations Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea, Department of Nuclear Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea
⨯
So Won Oh,

Affiliations Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea, Department of Nuclear Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea
⨯
Hyung-Jun Im,

Affiliations Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea, Department of Molecular Medicine and Biopharmaceutical Science, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea
⨯
Do Won Hwang,

Affiliations Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea, Institute of Radiation Medicine, Medical Research Center, Seoul National University, Seoul, Republic of Korea
⨯
Hyejin Kang,

Affiliation Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea
⨯
Boeun Lee,

Affiliations Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea, Department of Molecular Medicine and Biopharmaceutical Science, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea
⨯
Yun-Sang Lee,

Affiliation Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea
⨯
Jae Min Jeong,

Affiliation Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea
⨯
E. Edmund Kim,

Affiliations Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea, Department of Molecular Medicine and Biopharmaceutical Science, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea
⨯
June-Key Chung,

Affiliation Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea
⨯
Dong Soo Lee

* E-mail: dsl@plaza.snu.ac.kr (DSL); yk3181@snu.ac.kr (YKK)

Affiliations Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea, Department of Molecular Medicine and Biopharmaceutical Science, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea
⨯

In Vivo Imaging of mGluR5 Changes during Epileptogenesis Using [¹¹C]ABP688 PET in Pilocarpine-Induced Epilepsy Rat Model

Hongyoon Choi,
Yu Kyeong Kim,
So Won Oh,
Hyung-Jun Im,
Do Won Hwang,
Hyejin Kang,
Boeun Lee,
Yun-Sang Lee,
Jae Min Jeong,
E. Edmund Kim

Published: March 24, 2014
https://doi.org/10.1371/journal.pone.0092765

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