Early MEK1/2 Inhibition after Global Cerebral Ischemia in Rats Reduces Brain Damage and Improves Outcome by Preventing Delayed Vasoconstrictor Receptor Upregulation

Open Access

Peer-reviewed

Research Article

Sara Ellinor Johansson ,

* E-mail: sara.ellinor.johansson@regionh.dk

Affiliation Department of Clinical Experimental Research, Glostrup Research Institute, Glostrup Hospital, Glostrup, Denmark
⨯
Stine Schmidt Larsen,

Affiliation Department of Clinical Experimental Research, Glostrup Research Institute, Glostrup Hospital, Glostrup, Denmark
⨯
Gro Klitgaard Povlsen,

Affiliation Department of Clinical Experimental Research, Glostrup Research Institute, Glostrup Hospital, Glostrup, Denmark
⨯
Lars Edvinsson

Affiliations Department of Clinical Experimental Research, Glostrup Research Institute, Glostrup Hospital, Glostrup, Denmark, Division of Experimental Vascular Research, Department of Clinical Sciences, Lund University, Lund, Sweden
⨯

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Cerebral ischemia
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Neuronal death
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Ischemia
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Neuronal tuning
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Cerebral arteries
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Serotonin receptors
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Hippocampus
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Rats
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