Inhibiting Spinal Neuron-Astrocytic Activation Correlates with Synergistic Analgesia of Dexmedetomidine and Ropivacaine

Huang-Hui Wu; Jun-Bin Yin; Ting Zhang; Yuan-Yuan Cui; Yu-Lin Dong; Guo-Zhong Chen; Wen Wang

doi:10.1371/journal.pone.0092374

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Peer-reviewed

Research Article

Inhibiting Spinal Neuron-Astrocytic Activation Correlates with Synergistic Analgesia of Dexmedetomidine and Ropivacaine

Huang-Hui Wu ,

Contributed equally to this work with: Huang-Hui Wu, Jun-Bin Yin, Ting Zhang

Affiliation Department of Anesthesiology, Fuzhou General Hospital of Nanjing Military Region, Fuzhou, PR China
⨯
Jun-Bin Yin ,

Contributed equally to this work with: Huang-Hui Wu, Jun-Bin Yin, Ting Zhang

Affiliation Department of Anatomy, Histology and Embryology & K.K. Leung Brain Research Centre, Preclinical School of Medicine, Fourth Military Medical University, Xi’an, PR China
⨯
Ting Zhang ,

Contributed equally to this work with: Huang-Hui Wu, Jun-Bin Yin, Ting Zhang

Affiliation Department of Anatomy, Histology and Embryology & K.K. Leung Brain Research Centre, Preclinical School of Medicine, Fourth Military Medical University, Xi’an, PR China
⨯
Yuan-Yuan Cui,

Affiliation Department of Anatomy, Histology and Embryology & K.K. Leung Brain Research Centre, Preclinical School of Medicine, Fourth Military Medical University, Xi’an, PR China
⨯
Yu-Lin Dong,

Affiliation Department of Anatomy, Histology and Embryology & K.K. Leung Brain Research Centre, Preclinical School of Medicine, Fourth Military Medical University, Xi’an, PR China
⨯
Guo-Zhong Chen ,

* E-mail: cgzssq2000@sina.com (GZC); wangwen@fmmu.edu.cn (WW)

Affiliation Department of Anesthesiology, Fuzhou General Hospital of Nanjing Military Region, Fuzhou, PR China
⨯
Wen Wang

* E-mail: cgzssq2000@sina.com (GZC); wangwen@fmmu.edu.cn (WW)

Affiliation Department of Anatomy, Histology and Embryology & K.K. Leung Brain Research Centre, Preclinical School of Medicine, Fourth Military Medical University, Xi’an, PR China
⨯

Inhibiting Spinal Neuron-Astrocytic Activation Correlates with Synergistic Analgesia of Dexmedetomidine and Ropivacaine

Huang-Hui Wu,
Jun-Bin Yin,
Ting Zhang,
Yuan-Yuan Cui,
Yu-Lin Dong,
Guo-Zhong Chen,
Wen Wang

Published: March 21, 2014
https://doi.org/10.1371/journal.pone.0092374

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