Ubiquitin Ligase gp78 Targets Unglycosylated Prion Protein PrP for Ubiquitylation and Degradation

• Jia Shao ,

  Contributed equally to this work with: Jia Shao, Vitnary Choe

  Affiliation The First Affiliated Hospital, Nanchang University, Nanchang, Jiangxi, China

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• Vitnary Choe ,

  Contributed equally to this work with: Jia Shao, Vitnary Choe

  Affiliation Department of Molecular Medicine, the University of Texas Health Science Center, San Antonio, Texas, United States of America

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• Haili Cheng,

  Affiliation Department of Molecular Medicine, the University of Texas Health Science Center, San Antonio, Texas, United States of America

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• Yien Che Tsai,

  Affiliation Laboratory of Protein Dynamics and Signaling, National Cancer Institute, Frederick, Maryland, United States of America

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• Allan M. Weissman,

  Affiliation Laboratory of Protein Dynamics and Signaling, National Cancer Institute, Frederick, Maryland, United States of America

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• Shiwen Luo ,

  * E-mail: shiwenluo@ncu.edu.cn (SL); raoh@uthscsa.edu (HR)

  Affiliation The First Affiliated Hospital, Nanchang University, Nanchang, Jiangxi, China

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• Hai Rao

  * E-mail: shiwenluo@ncu.edu.cn (SL); raoh@uthscsa.edu (HR)

  Affiliation Department of Molecular Medicine, the University of Texas Health Science Center, San Antonio, Texas, United States of America

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